81819-14-9

Basic information

• Product Name: (4,5-diphenyloxazol-2-yl)methyl bromide
• Synonyms: (4,5-diphenyloxazol-2-yl)methyl bromide
• CAS NO: 81819-14-9
• Molecular Weight: 314.181
• Mol File: 81819-14-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4,5-diphenyloxazol-2-yl)methyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-diphenyloxazol-2-yl)methyl bromide(81819-14-9)
• EPA Substance Registry System: (4,5-diphenyloxazol-2-yl)methyl bromide(81819-14-9)

Safety Data

• Hazardous Substances Data: 81819-14-9(Hazardous Substances Data)

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 14224-99-8 2-methyl-4,5-diphenyloxazole 

Downstream Products

• 136451-77-9 methyl <3-<(4,5-diphenyl-2-oxazolyl)methoxy>phenoxy>acetate 
• 136451-71-3 methyl 3-[4-[(4,5-diphenyl-2oxazolyl)methoxy]phenyl]propanoate 
• 21256-18-8 3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid 
• 187992-62-7 1-[(4,5-diphenyloxazol-2-yl)methylthio]-1,2,3,4-tetrahydro-5-methoxycarbonylmethoxynaphthalene 
• 110703-64-5 [3-(4,5-Diphenyl-oxazol-2-ylmethyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid 
• 136451-70-2 3-[3-[(4,5-diphenyl-2-oxazolyl)methoxy]phenyl]propanoic acid 
• 143215-96-7 methyl 3-<3-<(4,5-diphenyl-2-oxazolyl)methoxy>phenyl>-2-propenoate 
• 143215-97-8 3-[3-[(4,5-Diphenyl-2-oxazolyl)-methoxy]phenyl]-2-propenoic acid 
• 147594-36-3 methyl <3-<2-cyano-2-(4,5-diphenyl-2-oxazolyl)ethyl>phenoxy>acetate 
• 147594-34-1 (E)-methyl <3-<2-cyano-2-(4,5-diphenyl-2-oxazolyl)ethenyl>phenoxy>acetate 

Relevant articles and documents

Synthesis of extended oxazoles II: Reaction manifold of 2-(halomethyl)-4,5-diaryloxazoles

2-(Halomethyl)-4,5-diphenyloxazoles are effective, reactive scaffolds which can be utilized for synthetic elaboration at the 2-position. Through substitution reactions, the chloromethyl analogue is used to prepare a number of 2-alkylamino-, 2-alkylthio-, and 2-alkoxy-(methyl) oxazoles. The 2-bromomethyl analogue offers a more reactive alternative to the chloromethyl compounds and is useful in the C-alkylation of a stabilized (malonate) carbanion as exemplified by a concise synthesis of Oxaprozin.

[2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters

Oxazole derivatives having Formula I or II are disclosed which are useful as inhibitors of mammalian blood platelet aggregation. STR1 Formula I and Formula XIX compounds are those wherein n is 7-9 and R is hydrogen or lower alkyl. Formula II compounds are those wherein R is hydrogen, lower alkyl or together with CO2 is tetrazol-1-yl; R1 is phenyl or thienyl; X is a divalent connecting group selected from the group consisting of CH2 CH2, CH=CH, and CH2 O; Y is a divalent connecting group attached to the 3 or 4 phenyl position selected from the group consisting of OCH2, CH2 CH2 and CH=CH. Formula XX compounds are those wherein the OCH2 CO2 R moiety is attached to the 3 or 4 phenyl position and R is hydrogen or lower alkyl.