81828-87-7

Basic information

• Product Name: Quinoline, 2-(2,4,6-trimethylphenyl)-
• CAS NO: 81828-87-7
• Molecular Formula: C18H17N
• Molecular Weight: 247.34
• Mol File: 81828-87-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Quinoline, 2-(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-(2,4,6-trimethylphenyl)-(81828-87-7)
• EPA Substance Registry System: Quinoline, 2-(2,4,6-trimethylphenyl)-(81828-87-7)

Safety Data

• Hazardous Substances Data: 81828-87-7(Hazardous Substances Data)

Upstream product

• 1613-37-2 Quinoline N-oxide 
• 2633-66-1 2-mesitylmagnesium bromide 
• 1667-01-2 2,4,6-Trimethylacetophenone 
• 552-89-6 2-nitro-benzaldehyde 
• 94005-04-6 2-nitro-2'.4'.6'-trimethyl-trans-chalcone 
• 2005-43-8 2-bromoquinoline 
• 5980-97-2 mesitylboronic acid 
• 74857-04-8 2,2'-diquinolyl ether 
• 612-62-4 2-Chloroquinoline 
• 91-22-5 quinoline 
• 527-60-6 Mesitol 
• 5806-59-7 mesityllithium 

Downstream Products

• 700-13-0 Trimethylhydroquinone 
• 101733-76-0 2-mesityl-quinoline-1-oxide 

Relevant articles and documents

Synthesis and characterization of an isopropylBippyPhos precatalyst

A review of our high throughput reaction screening data revealed that BippyPhos was frequently associated with successful outcomes in Buchwald – Hartwig amination reactions. A barrier to the wider use of this ligand, particularly among those performing sm

Dehydrogenative etherification homocoupling of heterocyclic N-oxides

A novel approach was developed for the dehydrogenative etherification homocoupling of heterocyclic N-oxides in the presence of silver oxide and PyBroP. Various substrates were well tolerated and the desired products were obtained in moderate to good yields. Generally, this reaction features excellent functional group compatibility, broad substrate scope and good regioselectivity.

Regioselective Chlorination of Quinoline N-Oxides and Isoquinoline N-Oxides Using PPh3/Cl3CCN

A novel method for the regioselective C2-chlorination of heterocyclic N-oxides has been developed. PPh3/Cl3CCN were used as chlorinating reagents and the desired N-heterocyclic chlorides were obtained smoothly in satisfactory yields. The reactions proceeded in a highly efficient and selective manner across a broad range of substrates demonstrating excellent functional group tolerance. In addition, this chlorination reaction can be used for the modification of N-heterocyclic scaffolds of appealing ligands and pharmaceuticals.