81861-40-7

Basic information

• Product Name: (Z)-2-Hydroxy-nonadec-10-enenitrile
• Synonyms: (Z)-2-Hydroxy-nonadec-10-enenitrile
• CAS NO: 81861-40-7
• Molecular Weight: 293.493
• Mol File: 81861-40-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-Hydroxy-nonadec-10-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Hydroxy-nonadec-10-enenitrile(81861-40-7)
• EPA Substance Registry System: (Z)-2-Hydroxy-nonadec-10-enenitrile(81861-40-7)

Safety Data

• Hazardous Substances Data: 81861-40-7(Hazardous Substances Data)

Upstream product

• 2423-10-1 Oleic aldehyde 
• 143-33-9 sodium cyanide 

Relevant articles and documents

Darmstoff Analogues. 2. Ring and Side-Chain Effects on Smooth-Muscle Contraction

2-cis-Δ8-Heptadecenyl-4-(hydroxymethyl)-1,3-dioxolane monosodium phosphate (1b) has been shown to be present as a major component of Darmstoff in mammalian intestine and to be a potent inducer for contraction of intestinal smooth muscle.The analogous 2-pentadecyl material 1a, also found abundantly in the intestine, is inactive.In this study, synthesis of phosphorylated hydroxymethyl-1,4-dioxanes, -tetrahydrofurans, -cyclopentanes, and -oxathiolanes bearing both oleyl and palmityl side chains is reported.Of these, 2-(hydroxymethyl)-5-cis-Δ8-heptadecenyl-1,4-dioxane monosodium phosphate (2b) exhibits about 12percent of the activity of 1b.Its pentadecyl analogue 2a, like 1a, is totally inactive, as are all other compounds prepared.The results indicate that Darmstoff-like compounds exhibit specific chemical requirements for activity and that where activity is encountered, the side-chain specificity noted in 1a and 1b can be preserved.