819075-95-1

Basic information

• Product Name: (S)-3-[(S)-2-(6-Chloro-benzooxazol-2-ylamino)-3-cyclohexyl-propionylamino]-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid
• CAS NO: 819075-95-1
• Molecular Weight: 543.038
• Mol File: 819075-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-[(S)-2-(6-Chloro-benzooxazol-2-ylamino)-3-cyclohexyl-propionylamino]-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-[(S)-2-(6-Chloro-benzooxazol-2-ylamino)-3-cyclohexyl-propionylamino]-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid(819075-95-1)
• EPA Substance Registry System: (S)-3-[(S)-2-(6-Chloro-benzooxazol-2-ylamino)-3-cyclohexyl-propionylamino]-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid(819075-95-1)

Safety Data

• Hazardous Substances Data: 819075-95-1(Hazardous Substances Data)

Upstream product

• 22876-20-6 6-chloro-2-mercaptobenzoxazole 
• 28443-50-7 2-amino-5-chlorophenol 
• 17193-39-4 methyl 3-cyclohexyl-L-alaninate hydrochloride 
• 3621-82-7 2,6-dichloro-1,3-benzoxazole 
• 819076-55-6 3-benzyloxycarbonylamino-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid tert-butyl ester 

Relevant articles and documents

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3

A series of Nα-2-benzoxazolyl-α-amino acid-(arylaminoethyl)amides were identified as potent, selective, and noncovalent inhibitors of cathepsin S. Structure-activity relationships including strategies for modulating the selectivities among cathepsins S, K, and L, and in vivo pharmacokinetics are discussed. A X-ray structure of compound 3 bound to the active site of cathepsin S is also reported.