81964-78-5Relevant articles and documents
Aminolysis of isatin and N-acetyl isatin in acetonitrile and mixed acetonitrile-water solvents
Ibrahim, Mahmoud F.,Al-Karewi, Asma A.A.,Khattab, Sherine N.,Hamed, Ezzat A.,El-Faham, Ayman
, p. 8029 - 8038 (2015/02/19)
The reactions of N-acetyl isatin and N-propionyl isatin with morpholine, piperazine and diethylamine in acetonitrile underwent nucleophilic substitution reactions at the amide linkage with ring opening process to give N-[2-(2-amino-2-oxo-acetyl)phenyl]ace