81968-62-9

Basic information

• Product Name: 4(15),5,10(14)-Germacratrien-1-ol
• Synonyms: 4(15),5,10(14)-Germacratrien-1-ol;(7S)-7-isopropyl-4,10-diMethylenecyclodec-5-enol
• CAS NO: 81968-62-9
• Molecular Formula: C15H24O
• Molecular Weight: 220
• Mol File: 81968-62-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 321.1±42.0 °C(Predicted)
• Appearance: /
• Density: 0.91±0.1 g/cm3(Predicted)
• PKA: 14.76±0.40(Predicted)
• CAS DataBase Reference: 4(15),5,10(14)-Germacratrien-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4(15),5,10(14)-Germacratrien-1-ol(81968-62-9)
• EPA Substance Registry System: 4(15),5,10(14)-Germacratrien-1-ol(81968-62-9)

Safety Data

• Hazardous Substances Data: 81968-62-9(Hazardous Substances Data)

Usage

General Description

4(15),5,10(14)-Germacratrien-1-ol is a sesquiterpene alcohol found in certain plants and essential oils. It is a colorless or pale yellow liquid with a floral and woody odor. This chemical compound has been identified in various aromatic plants such as turmeric, ginger, and ylang ylang. It possesses antifungal and antibacterial properties, making it a potential candidate for use in pharmaceutical and cosmetic applications. Additionally, 4(15),5,10(14)-Germacratrien-1-ol has been investigated for its potential anti-inflammatory and antioxidant activities, further adding to its potential pharmaceutical and therapeutic uses.

Upstream product

• 23986-74-5 germacrene D 
• 105453-16-5 germacrene D 
• 70560-77-9 (E)-(1R,4S,10R)-4-Isopropyl-1-methyl-7-methylene-11-oxa-bicyclo[8.1.0]undec-5-ene 

Downstream Products

• 123163-72-4 (-)-periplanone C 

Relevant articles and documents

EREMOPHILENE AND GERMACRENE DERIVATIVES FROM SENECIO GLANDULOSO-PILOSUS

Senecio glanduloso-pilosus afforded in addition to known compounds a new eremophilene derivative and a hydroperoxide from germacrene D. - Key Word Index: Senecio glanduloso-pilosus; Compositae; sesquiterpenes; eremophilene derivative; germacrene hydroperoxide.

Total synthesis of (-)-periplanones C and D. Their pheromonal activities against three Periplaneta species

Total synthesis of(-)-periplanones C [(-)-PC; 1] and D [(-)-PD; 2] was achieved starting from (-)-germacrene D via 7 and 8 steps, respectively, according to the similar route on syntheses of racemic PC and PD. The 1H NMR and GC mass spectra of 2 unambiguously determined the structure of the natural sample of PD which was isolated from Periplaneta fuliginosa. Bioassay of synthetic samples of 1 and 2 was carried oat against males of P. fuliginosa, P. americana, and P. japonica. 10-9 g of 1 elicited significant response in males of P. americana and P. japonica. 10-10 g of 2 elicited strong response in P. fuliginosa males, whereas it showed significantly weak response against males of P. americana and P. japonica. Almost same degree of activities was observed between 1 and 2 against males of P. americana and P. japonica at 10-10 g dose.

Constituents of Torilis japonica D.C. I. Isolation and Optical Purity of Germacra-4(15),5(E),10(14)-trien-1β-ol

Humulene (I), (-)-germacrene-D (II), and (-)-germacra-4(15),5(E),10(14)-trien-1β-ol (III) were isolated from the fruits of Torilis japonica.The latter two compounds (II and III) were determined to have optical purities of about 40 and 30percent, respectively.Keywords-Torilis japonica; humulene; germacrene-D; germacra-4(15),5(E),10(14)-trien-1β-ol; optical purity