82-86-0 Usage
Description
Acenaphthenequinone is a member of the class of orthoquinones that is the 1,2-dioxo derivative of acenaphthene. It is characterized by its ochre powder and granules appearance.
Uses
Used in Pharmaceutical Industry:
Acenaphthenequinone is used as an intermediate in the manufacturing of dyes and pharmaceuticals. It plays a crucial role in the synthesis of various drugs and dyes, contributing to the development of new and improved products in the pharmaceutical industry.
Used in Chemical Research:
Acenaphthenequinone is used as a drug and therapeutic agent in chemical research. Its unique chemical properties make it a valuable compound for studying various biological and chemical processes, leading to the discovery of new therapeutic agents and applications.
Used in Bioimaging:
Acenaphthenequinone is used in the preparation of turn-on sensors for cysteine/homocysteine and its application in bioimaging. This allows for the detection and monitoring of these important biomolecules, providing valuable insights into their role in various biological processes and diseases.
Used in Acetylcholinesterase Inhibition:
Acenaphthenequinone is used in the preparation of acetylcholinesterase inhibitory agents. These agents are important in the treatment of various neurological disorders, such as Alzheimer's disease, by inhibiting the enzyme acetylcholinesterase and increasing the levels of the neurotransmitter acetylcholine in the brain.
Safety Profile
Moderately toxic by an unspecifiedroute. When heated to decomposition it emits acrid smokeand irritating vapors.
Purification Methods
Extract it with, then recrystallise it twice from *C6H6. Dry it in vacuo. [LeFevre et al. J Chem Soc 974 1963, Beilstein 7 IV 2498.]
Check Digit Verification of cas no
The CAS Registry Mumber 82-86-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82-86:
(4*8)+(3*2)+(2*8)+(1*6)=60
60 % 10 = 0
So 82-86-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H8O2/c13-10-6-8-3-1-2-7-4-5-9(11(7)8)12(10)14/h1-3,6H,4-5H2
82-86-0Relevant articles and documents
The special role of B(C6F5)3 in the single electron reduction of quinones by radicals
Tao, Xin,Daniliuc, Constantin G.,Knitsch, Robert,Hansen, Michael Ryan,Eckert, Hellmut,Lübbesmeyer, Maximilian,Studer, Armido,Kehr, Gerald,Erker, Gerhard
, p. 8011 - 8018 (2018/11/03)
In the presence of two molar equiv. of B(C6F5)3p-benzoquinone reacts with persistent radicals TEMPO, trityl or decamethylferrocene by single electron transfer to give doubly O-borylated benzosemiquinone radical anions with
Kinetic studies of acenaphthene oxidation catalyzed by N-Hydroxyphthalimide
Opeida,Litvinov,Kushch,Kompanets,Shendrik
, p. 515 - 524 (2013/07/26)
The acenaphthene oxidation with molecular oxygen in the presence of N-hydroxyphthalimide (NHPI) has been investigated. It is shown that the main oxidation product is acenaphthene hydroperoxide. The phthalimide-N-oxyl (PINO) radical has been generated in situ from its hydroxyimide parent, NHPI, by oxidation with iodobenzenediacetate. The rate constant of H-abstraction (k H) from acenaphthene by PINO has been determined spectroscopically in acetonitrile. The kinetic isotope effect and the activation parameters have also been measured. On the basis of the results of our studies and available published literature data, a plausible mechanism for the oxidation process of acenaphthene with dioxygen catalyzed by NHPI was discussed.
New recoverable organoselenium catalyst for hydroperoxide oxidation of organic substrates
Wojtowicz, Halina,Soroko, Grazyna,Mlochowski, Jacek
, p. 2000 - 2010 (2008/09/21)
New benzisoselenazol-3(2H)-one covalently bounded to a silica support was synthesized and characterized. It was used as an effective, selective, and easy-to-regenerate catalyst for t-BuOOH and H2O2 oxidation of alkyl arenes to alkyl aryl ketones, aromatic aldehydes to arene carboxylic acids, and sulfoxides and/or sulfones. Copyright Taylor & Francis Group, LLC.