82003-82-5

Basic information

• Product Name: 3-Methyl-1-phenethyl-4-piperidinone
• Synonyms: 3-Methyl-1-phenethyl-4-piperidinone;3-Methyl-1-phenethyl-4-piperidinone（WS204371）
• CAS NO: 82003-82-5
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.30676
• Mol File: 82003-82-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 111-112℃
• Boiling Point: 123-125 °C(Press: 0.3 Torr)
• Appearance: /
• Density: 1.023
• PKA: 8.06±0.40(Predicted)
• CAS DataBase Reference: 3-Methyl-1-phenethyl-4-piperidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-1-phenethyl-4-piperidinone(82003-82-5)
• EPA Substance Registry System: 3-Methyl-1-phenethyl-4-piperidinone(82003-82-5)

Safety Data

• Hazardous Substances Data: 82003-82-5(Hazardous Substances Data)

Upstream product

• 22280-02-0 3-methylpyridin-4-ol 
• 17376-04-4 2-phenethyl iodide 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 129164-47-2 trans-N-(2-phenylethyl)-3-methyl-N'-phenyl-N'ethylisonipecotinamide 
• 129164-44-9 trans-1-(2-phenylethyl)-3-methylisonipecotic acid 
• 129164-44-9 cis-1-(2-phenylethyl)-3-methylisonipecotic acid 
• 129164-35-8 trans-1-(2-phenylethyl)-3-methylisonipecotinamide 
• 101344-51-8 Furan-2-carboxylic acid (2-methoxy-phenyl)-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-amide 
• 101344-51-8 Furan-2-carboxylic acid (2-methoxy-phenyl)-((3R,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-amide 
• 101344-94-9 Furan-2-carboxylic acid (2-chloro-phenyl)-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-amide 
• 101344-94-9 Furan-2-carboxylic acid (2-chloro-phenyl)-((3R,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-amide 
• 101344-46-1 Furan-2-carboxylic acid (2-fluoro-phenyl)-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-amide 
• 101344-38-1 N-(2-Chloro-phenyl)-2-methoxy-N-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-propionamide 
• 101344-38-1 N-(2-Chloro-phenyl)-2-methoxy-N-((3R,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-propionamide 
• 101345-13-5 N-(2-Fluoro-phenyl)-2-methoxy-N-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-propionamide 
• 101345-11-3 2-Methoxy-N-(2-methoxy-phenyl)-N-((3S,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-propionamide 
• 101345-11-3 2-Methoxy-N-(2-methoxy-phenyl)-N-((3R,4R)-3-methyl-1-phenethyl-piperidin-4-yl)-propionamide 

Relevant articles and documents

A process for preparing 3 - methyl - 1 - phenethyl piperidine - 4 - one or 1 - phenethyl piperidine - 4 - one method

The invention discloses a method for preparing 3-mehtyl-1-phenethyl piperidine-4-ketone or 1-phenethyl piperidine-4-ketone. The method starts from easily-obtained 3-substituted pyridine-4-alcohol, sodium borohydride is selectively reduced into allyl alcohol after 3-substituted pyridine-4-alcohol forms quaternary ammonium together with phenethyl-2-halide, and 3-substitute-1-phenethyl piperidine-4-ketone is obtained then after isomerization. The synthetic method is easy, convenient to use, practical, high in operability and beneficial to further large-scale production.