820222-48-8

Basic information

• Product Name: Spiro[3.4]octan-5-one, 6,6-dimethyl- (9CI)
• Synonyms: Spiro[3.4]octan-5-one, 6,6-dimethyl- (9CI)
• CAS NO: 820222-48-8
• Molecular Formula: C10H16O
• Molecular Weight: 152.23344
• Product Categories: CYCLOPENTANE
• Mol File: 820222-48-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[3.4]octan-5-one, 6,6-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[3.4]octan-5-one, 6,6-dimethyl- (9CI)(820222-48-8)
• EPA Substance Registry System: Spiro[3.4]octan-5-one, 6,6-dimethyl- (9CI)(820222-48-8)

Safety Data

• Hazardous Substances Data: 820222-48-8(Hazardous Substances Data)

Upstream product

• 10468-36-7 Spiro<3.4>octan-5-on 
• 74-88-4 methyl iodide 

Downstream Products

• 820222-59-1 (+/-)-(3aR,6aR)-3a,6,6a-trimethyl-1,2,3,3a,4,6a-hexahydro-pentalene 
• 820222-63-7 (+/-)-(3aR,6aR)-3a,6a-dimethyl-hexahydro-pentalen-1-one 
• 820222-45-5 6,6-dimethyl-spiro[3.4]octan-5-ol 

Relevant articles and documents

Synthesis and rearrangement of [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols: A general access to bicyclo[3.3.0]octenes (hexahydropentalenes)

Several new Grignard reagents based on substituted cyclobutanes have been generated and added to cyclobutanones to yield mono- to trimethylated [1,1′-bicyclobutyl]-1-ols. Mono- to trimethylated spiro[3.4]octan-5-ols have been prepared from the parent ketone via alkylation and/or addition reactions. Upon treatment with acid, all [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols rearrange to yield a single bicyclo[3.3.0]octene. Mono- to trimethylated [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols have been synthesized and rearranged to yield a single bicyclo[3.3.0]octene in each case. Examples are 42, 43, 44 and 45.