82160-07-4 Usage
Description
(S)-(-)-1-METHYL-2-(1-NAPHTHYLAMINOMETHYL)PYRROLIDINE, also known as (S)-1-Methyl-2-[(α-naphthylamino)methyl]pyrrolidine, is a chiral amine compound characterized by its unique molecular structure. It is a versatile catalyst with a naphthylamine group attached to a pyrrolidine ring, which contributes to its enantioselective properties. (S)-(-)-1-METHYL-2-(1-NAPHTHYLAMINOMETHYL)PYRROLIDINE plays a crucial role in the synthesis of various chiral molecules, particularly in the production of chiral aldehydes.
Uses
Used in Pharmaceutical Industry:
(S)-(-)-1-METHYL-2-(1-NAPHTHYLAMINOMETHYL)PYRROLIDINE is used as an efficient enantioselective catalyst for the synthesis of chiral aldehydes. These chiral aldehydes are essential building blocks in the production of various pharmaceutical compounds, including drugs with specific therapeutic effects. The enantioselective nature of this catalyst ensures that the desired chiral products are obtained with high selectivity, which is crucial for the development of effective and safe medications.
Used in Chemical Synthesis:
In the field of chemical synthesis, (S)-(-)-1-METHYL-2-(1-NAPHTHYLAMINOMETHYL)PYRROLIDINE serves as a valuable enantioselective catalyst for the preparation of chiral compounds. Its ability to selectively catalyze reactions involving the formation of chiral centers is highly beneficial for the synthesis of complex organic molecules, such as natural products, agrochemicals, and specialty chemicals. This catalyst's efficiency and selectivity make it a preferred choice for chemists working on the development of enantioselective synthetic routes.
Used in Research and Development:
(S)-(-)-1-METHYL-2-(1-NAPHTHYLAMINOMETHYL)PYRROLIDINE is also utilized in research and development settings, where it is employed to study the mechanisms of enantioselective catalysis and to develop new synthetic methodologies. Its unique structure and catalytic properties make it an interesting subject for academic research, as well as for the development of innovative industrial processes.
Check Digit Verification of cas no
The CAS Registry Mumber 82160-07-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,1,6 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 82160-07:
(7*8)+(6*2)+(5*1)+(4*6)+(3*0)+(2*0)+(1*7)=104
104 % 10 = 4
So 82160-07-4 is a valid CAS Registry Number.
82160-07-4Relevant articles and documents
Base-catalysed asymmetric hydroamination/cyclisation of aminoalkenes utilising a dimeric chiral diamidobinaphthyl dilithium salt
Martinez, Patricia Horrillo,Hultzsch, Kai C.,Hampel, Frank
, p. 2221 - 2223 (2007/10/03)
A dimeric proline derived diamidobinaphthyl dilithium salt represents the first example of a chiral main group metal based catalyst for asymmetric hydroamination/cyclisation reactions of aminoalkenes. The Royal Society of Chemistry 2006.
THE ENANTIOFACE-DIFFERENTIATING METHYLATION OF THE N-BENZYLIDENE-DL-PHENYLALANINE METHYL ESTER IN THE PRESENCE OF CHIRAL LITHIUM AMIDES
Yamashita, Tetsushi,Mitsui, Hitoshi,Watanabe, Hiroyuki,Nakamura, Nobuo
, p. 961 - 962 (2007/10/02)
The asymmetric methylation of the N-benzylidene-DL-phenylalanine methyl ester was carried out in the presence of lithium salts of secondary amines derived from (S)-proline.The lithium amides of poly-(imino-1-isobutylethylene) and its corresponding low-molecular-weight model compound, derived from (S)-leucine, were similarly used in order to examine the polymer effects with regard to the stereoselectivity.
