82220-45-9

Basic information

• Product Name: methanesulfonic phosphoric anhydride, diisopropyl ester
• Synonyms: methanesulfonic phosphoric anhydride, diisopropyl ester
• CAS NO: 82220-45-9
• Molecular Weight: 260.248
• Mol File: 82220-45-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methanesulfonic phosphoric anhydride, diisopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: methanesulfonic phosphoric anhydride, diisopropyl ester(82220-45-9)
• EPA Substance Registry System: methanesulfonic phosphoric anhydride, diisopropyl ester(82220-45-9)

Safety Data

• Hazardous Substances Data: 82220-45-9(Hazardous Substances Data)

Upstream product

• 67711-52-8 1-(diisopropoxyphosphinyl)imidazole 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 1666-10-0 N-phenyl-N-diisopropylphosphoramidate 
• 82220-46-0 anilinium methanesulfonate 
• 75-75-2 methanesulfonic acid 
• 26955-63-5 diisopropyl methyl phosphate 

Relevant articles and documents

Phosphoric and Phosphinic Sulfonic Anhydrides - Reinvestigation and Corrections. Novel Methods of Synthesis

Earlier works from this and other laboratories on phosphoric and phosphinic sulfonic anhydrides have been reinvestigated.It was found that no single reaction described in the past provides a general method for the production of mixed anhydrides RR'P(O)SO2R'' (3) in high yields of isolated products.The following three efficient synthetic procedures leading to pure anhydrides 3 are described: a) Trifluoromethanesulfonic acid promoted reaction of phosphinic acid 9 with sulfonic triazolides 10. b) Reaction of phosphinic and phosphoric imidazolides 13 with sulfonic acid 6. c) Reaction of 13 with sulfonic anhydride 15.All methods result in high yields.Some chemical properties of the anhydrides 3 are described.