82263-48-7

Basic information

• Product Name: Cyclopropanecarboxaldehyde, 2-phenyl-, (1R,2R)- (9CI)
• Synonyms: Cyclopropanecarboxaldehyde, 2-phenyl-, (1R,2R)- (9CI)
• CAS NO: 82263-48-7
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.1858
• Product Categories: ALDEHYDE
• Mol File: 82263-48-7.mol
• Article Data: 34

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarboxaldehyde, 2-phenyl-, (1R,2R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxaldehyde, 2-phenyl-, (1R,2R)- (9CI)(82263-48-7)
• EPA Substance Registry System: Cyclopropanecarboxaldehyde, 2-phenyl-, (1R,2R)- (9CI)(82263-48-7)

Safety Data

• Hazardous Substances Data: 82263-48-7(Hazardous Substances Data)

Upstream product

• 25226-98-6 trans-cinnamaldehyde diethylacetal 
• 82263-49-8 (2R,4R,5S)-3,4-Dimethyl-5-phenyl-2-((1S,2S)-2-phenyl-cyclopropyl)-oxazolidine 
• 14371-10-9 (E)-3-phenylpropenal 
• 82215-37-0 (2R,4R,5S)-3,4-Dimethyl-5-phenyl-2-((E)-styryl)-oxazolidine 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 73566-21-9 1-phenyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethan-1-one 
• 100-52-7 benzaldehyde 
• 936-98-1 ((S)-2-Phenyl-cyclopropyl)-methanol 
• 110659-58-0 (1S,2S)-trans-1-(hydroxymethyl)-2-phenylcyclopropane 
• 212066-31-4 (1'R,2'R)-(-)-1-(2-phenylcyclopropyl)ethanone 
• 110659-58-0 (1R,2R)-1-hydroxymethyl-2-phenylcyclopropane 

Downstream Products

• 3471-10-1 (1R,2R)-trans-2-phenyl-1-cyclopropanecarboxylic acid 
• 34271-31-3 trans-2-phenylcyclopropanecarbaldehyde 
• 158360-21-5 3E-<(1S,2R)-2-phenyl-1-cyclopropyl>-2-propen-1-ol 
• 161344-89-4 3E-<(1R,2S)-2-phenyl-1-cyclopropyl>-2-propen-1-ol 
• 185135-46-0 ethyl 3E-<(1S,2R)-2-phenyl-1-cyclopropyl>prop-1-enoate 
• 161344-86-1 ethyl 3E-<(1R,2S)-2-phenyl-1-cyclopropyl>prop-1-enoate 
• 22467-91-0 cis-1-(trans-β-Ethoxycarbonylvinyl)-2-phenylcyclopropan 
• 110659-58-0 (1R,2R)-1-hydroxymethyl-2-phenylcyclopropane 
• 625455-49-4 (1R,1’S,2’S)-1-(2-phenylcyclopropyl)but-3-en-1-ol 
• 321906-18-7 trans-(2-vinylcyclopropyl)benzene 
• 17955-08-7 cis-2-Phenyl-vinyl-cyclopropan 

Relevant articles and documents

Skeletally Tunable Seven-Membered-Ring Fused Pyrroles

We describe a copper-mediated method that enables the synthesis of seven-membered-ring fused pyrroles (7-mrFPs). The protocol proceeds via an in situ spiro-intermediate ring expansion and tolerates a library of 7-mrFP derivatives with a broad range of functional groups in a simple step with tangible parameters and substrate adaptations. These rare 7-mrFPs are now accessible on a millimolar scale, and selected examples exhibit high antioxidant activity.

Visible-Light Controlled Divergent Catalysis Using a Bench-Stable Cobalt(I) Hydride Complex

While the use of visible light in conjunction with transition metal catalysis offers powerful opportunities to switch between on/-off states of catalytic activity, the next frontier would be the ability to switch the actual function of the catalyst and resulting products. Here we report such an example of multi-dimensional catalysis. Featuring an easily prepared, bench-stable cobalt(I) hydride complex in conjunction with pinacolborane, we can switch the reaction outcome between two widely employed transformations, olefin migration and hydroboration, with visible light as the trigger.

Lewis Acid Catalyzed Annulation of Cyclopropane Carbaldehydes and Aryl Hydrazines: Construction of Tetrahydropyridazines and Application Toward a One-Pot Synthesis of Hexahydropyrrolo[1,2- b]pyridazines

In this report, a facile synthesis of tetrahydropyridazines via a Lewis acid catalyzed annulation reaction of cyclopropane carbaldehydes and aryl hydrazines has been demonstrated. Moreover, the generated tetrahydropyridazine further participated in a cycloaddition reaction with donor-acceptor cyclopropanes to furnish hexahydropyrrolo[1,2-b]pyridazines. We also performed these two steps in one pot in a consecutive manner. In addition, a monodecarboxylation reaction of hexahydropyrrolo[1,2-b]pyridazine was achieved with a good yield.