82353-63-7Relevant articles and documents
STEREOSELECTIVE SYNTHESIS OF (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYL-PENTANOIC ACID, AN AMINO ACID CONSTITUENT OF BLEOMYCIN, BY ALDOL CONDENSATION
Narita, Masatoshi,Otsuka, Masami,Kobayashi, Susumu,Ohno, Masaji
, p. 525 - 528 (2007/10/02)
(2S,3S,4R)-4-Amino-3-hydroxy-2-methylpentanoic acid, a novel amino acid constituent of bleomycin, has been synthesized stereoselectively through aldol condensation of (R)-2-aminopropionaldehyde derivatives and E-vinyloxyboranes.