82356-80-7

Basic information

• Product Name: 1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE
• Synonyms: DI-N-BUTYLTETRAMETHYLDISILAZANE;DI-N-BUTYL-1,1,3,3-TETRAMETHYLDISILAZANE;1,3-DI-N-BUTYL-1,1,3,3-TETRAMETHYLDISILAZANE;1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE
• CAS NO: 82356-80-7
• Molecular Formula: C12H31NSi2
• Molecular Weight: 245.55
• Mol File: 82356-80-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 81 °C
• Flash Point: 86°C
• Appearance: /
• Density: 0.8
• Vapor Pressure: 0.0206mmHg at 25°C
• Refractive Index: 1.4353
• CAS DataBase Reference: 1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE(82356-80-7)
• EPA Substance Registry System: 1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE(82356-80-7)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3267
• TSCA: No
• Hazardous Substances Data: 82356-80-7(Hazardous Substances Data)

Usage

General Description

1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is a chemical compound with the molecular formula C14H36N2Si2. It is a clear, colorless liquid that is commonly used as a reagent in organic synthesis. This chemical is often employed as a silylation reagent, and is particularly useful for the derivatization of polar functional groups. Its ability to protect hydroxyl, amino, and carboxylic acid groups from unwanted reactions makes it a valuable tool in organic chemistry research. Additionally, 1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is also used as a precursor in the production of silicone polymers and as a sealant in certain applications. Overall, this chemical has a wide range of uses in various industries due to its versatile reactivity and properties.

InChI:InChI=1/C12H31NSi2/c1-7-9-11-14(3,4)13-15(5,6)12-10-8-2/h13H,7-12H2,1-6H3

Upstream product

• 1000-50-6 butyldimethylsilyl chloride 

Relevant articles and documents

Synthesis and characterization of dibutyltetramethyldisilazane-bonded silica phases for reversed-phase high-performance liquid chromatography

A new silane, di-n-butyltetramethyldisilazane (DBTMDS), has been synthesized. Silanizations withh DBTMDS of a narrow-pore and a wide-pore silica yielded relatively high concentrations of bonded n-butyl ligands, of 4.22 and 4.09 μmol/m2, respectively. The chromatographic properties of the n-butyl bonded phase (C4-NH), synthesized with DBTMDS, were compared with n-butyl bonded phases (C4-CL) synthesized with n-butyldimethylchlorosilane (BDMCS) and Vydac-C4 under the same chromatographic conditions. The adsorption of basic compounds including N,N-diethylaniline (N,N-DEA), dansylarginine (Dns-Arg), and (phenyithio)hydantoin-arginine (PTH-Arg), as well as several polypeptides and small proteins including angiotensin I, angiotensin II, and lysozyme, was shown to be less for the C4-NH sorbents than for C4-CL and Vydac-C4 sorbents. While the S value for the basic protein lysozyme was significantly lower on the wide-pore C4-NH sorbent, the S and log k0 values for a range of selected proteins were comparable to those obtained with the Vydac-C4 sorbent. The tests of hydrolytic stability of the bonded phases showed significantly greater stability for the C4-NH sorbents than for the C4-CL sorbents under isocratic mobile-phase conditions of 10% and 40% acetonitrile with 0.1% TFA.