82359-63-5Relevant articles and documents
Probes for Narcotic Receptor Mediated Phenomena. 9. Synthesis of (+/-)-(3α,6aα,11aβ)-1,3,4,5,6,11a-Hexahydro-2-methyl-2H-3,6a-methanobenzofuroazocin-10-ol, an Oxide-Bridged 5-(m-Hydroxyphenyl)morphan
Burke, Terrence R.,Jacobson, Arthur E.,Rice, Kenner C.,Weissman, Ben Avi,Huang, Hsueh-Cheng,Silverton, J. V.
, p. 748 - 751 (2007/10/02)
The synthesis of racemic (3α,6aα,11aβ)-1,3,4,5,6,11a-hexahydro-2-methyl-2H-3,6a-methanobenzofuroazocin-10-ol (2d) is described.The route used acid-catalyzed ring closure of enamine 5 to yield the unsaturated phenylmorphan 6.Conversion of 6 to oxide
4-Aryl-4-piperidinecarbinols
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, (2008/06/13)
4-Aryl-4-piperidinecarbinols, for example, STR1 useful as antidepressants and, in some cases, as anorectic agents.
STUDIES DIRECTED TOWARDS THE TOTAL SYNTHESIS OF MORPHINE ALKALOIDS
Evans, D. A.,Mitch, C. H.
, p. 285 - 288 (2007/10/02)
Application of metallated enamines to the synthesis of morphine related congeners is reported.A formal total synthesis of (+/-)-morphine has been completed.