82453-26-7

Basic information

• Product Name: 4(1H)-Cinnolinone, 3-[(1E)-2-phenylethenyl]-
• CAS NO: 82453-26-7
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.284
• Mol File: 82453-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Cinnolinone, 3-[(1E)-2-phenylethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Cinnolinone, 3-[(1E)-2-phenylethenyl]-(82453-26-7)
• EPA Substance Registry System: 4(1H)-Cinnolinone, 3-[(1E)-2-phenylethenyl]-(82453-26-7)

Safety Data

• Hazardous Substances Data: 82453-26-7(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 82452-98-0 3-iodo-4(1H)-cinnolinone 
• 18514-84-6 4(1H)-cinnolon 

Relevant articles and documents

SOME REACTIONS OF 3-HALOGENOCINNOLINES CATALYSED BY PALLADIUM COMPOUNDS

3-Bromo-or 3-iodo-cinnoline (and 4-substituted analogues ) are condensed with terminal alkynes in the presence of Pd and Cu compounds as catalysts to give the 3-alkynyl-derivatives.When 4-chloro- or 4-phenoxy-compounds are used, the products react with amines, in the presence of copper(I) iodide, to form pyrrolocinnolines and with hydrazines to give either the same ring system or a pyrazolocinnoline.Hydrolysis of 3-alkynyl-4phenoxycinnoline to 3-alkynyl-4(1H)-cinnolinone, followed by cyclisation, yields the furocinnoline.Attempts to condense 3-halogenocinnolines with alkenes gave variable results: 3-phenyl ethenyl- and 3(2-pyridylethenyl)-4-(1H)-cinnolinones were obtained but 3-bromocinnoline gave the 3,3'-bicinnolinyl.Action of palladium acetate in the presence of ethyl acrylate converted 3-bromo-4-phenoxycinnoline into benzofurocinnoline and 3-bromo-4-phenylaminocinnoline into indolocinnoline.