82461-15-2

Basic information

• Product Name: beta-allyl-beta-methylphenethyl alcohol
• Synonyms: beta-allyl-beta-methylphenethyl alcohol;β-Methyl-β-(2-propenyl)benzeneethanol;Einecs 279-968-3
• CAS NO: 82461-15-2
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 279-968-3
• Mol File: 82461-15-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 271.85-272℃ at 101.325kPa
• Appearance: /
• Vapor Pressure: 0.085Pa at 20℃
• CAS DataBase Reference: beta-allyl-beta-methylphenethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: beta-allyl-beta-methylphenethyl alcohol(82461-15-2)
• EPA Substance Registry System: beta-allyl-beta-methylphenethyl alcohol(82461-15-2)

Safety Data

• Hazardous Substances Data: 82461-15-2(Hazardous Substances Data)

Upstream product

• 492-37-5 hydratropic acid 
• 76403-17-3 (+/-)-2-methyl-2-phenyl-4-pentenoic acid 
• 57625-76-0 methyl 2-methyl-2-phenyl-4-pentenoate 
• 101-41-7 benzeneacetic acid methyl ester 
• 115913-99-0 N-(2-methyl-2-phenyl-4-pentenylidene)allylamine 
• 115913-92-3 N-allyl-N-phenyl-2-phenyl-1-propenylamine 
• 100747-85-1 N-phenyl-2-methyl-2-phenyl-4-pentenylideneamine 
• 34713-70-7 2-Phenylpropanal 
• 1823-91-2 1-phenylethyl cyanide 
• 104367-49-9 2-methyl-2-phenylpent-4-enenitrile 
• 24401-39-6 2-methyl-2-phenyl-pentenal 

Downstream Products

• 82461-14-1 2.4-dimethyl-4-phenyl-tetrahydrofuran 
• 24401-39-6 2-methyl-2-phenyl-pentenal 
• 42762-64-1 trans-2-methyl-2-phenylpent-3-enal 
• 849353-92-0 (1-methoxymethyl-1-methylbut-3-enyl)benzene 
• 413603-44-8 allyl-{1-[4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester 
• 235419-92-8 allyl-[1-(4-hydroxy-3-methyl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester 
• 413603-45-9 allyl-[1-(3-methyl-4-oxo-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester 
• 413603-43-7 4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-3-phenyl-butyraldehyde 
• 558442-44-7 2-methyl-2-phenylpent-4-enyl acetate 

Relevant articles and documents

Radical Aryl Migration from Boron to Carbon

Radical aryl migration reactions represent a unique type of organic transformations that involve the intramolecular migration of an aryl group from a carbon or heteroatom to a C- or heteroatom-centered radical through a spirocyclic intermediate. Various elements, including N, O, Si, P, S, Sn, Ge, and Se, have been reported to participate in radical aryl migrations. However, radical aryl migration from a boron center has not been reported to date. In this communication, radical 1,5-aryl migration from boron to carbon in aryl boronate complexes is presented. C-radicals readily generated through radical addition onto alkenyl aryl boronate complexes are shown to engage in 1,5-aryl migration reactions to provide 4-aryl-alkylboronic esters. As boronate complexes can be generatedin situby the reaction of alkenylboronic acid esters with aryl lithium reagents, the aryl moiety is readily varied, providing access to a series of arylated products starting from the same alkenylboronic acid ester via divergent chemistry. Reactions proceed with high diastereoselectivity under mild conditions, and also the analogous 1,4-aryl shifts are feasible. The suggested mechanism is supported by DFT calculations.

Decarboxylative allylations of ester enolate equivalents

A variety of ester enolate equivalents are generated in situ and undergo α-allylation in high yields via palladium-catalyzed decarboxylative allylation. The transformations are complete within very short reaction times under ambient conditions. Synthesis of α-allylated acyl derivatives provides access to other carboxylic acid and alcohol derivatives via acyl group substitution or reduction. This journal is

1,1,1-TRIFLUORO-4-PHENYL-4-METHYL-2-(1H-PYRROLO

Compounds of Formula (IA), IB), IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.