82500-59-2Relevant articles and documents
SYNTHESIS OF 1,2,4-TRIAZINO- AND IMIDAZOQUINOLINE DERIVATIVES
Slouka, Jan,Bekarek, Vojtech,Nalepa, Karel,Lycka, Antonin
, p. 2628 - 2634 (2007/10/02)
o-Nitrophenylpyruvic acid thiosemicarbazone (I) has been cyclized to 2-thio-5-(o-nitrobenzyl)-6-azauracil (II) which has been transformed in 5-quinolin-3-one (VI).Compound VI is transformed in acid medium to 1-amino-1,2-dihydroimidazoquinolin-2-one (VIII) via the tautomer VII, and in boiling acetic acid it gives the acetylamino derivative IX.The N-amino derivative VIII reacts with carbonyl compounds to give the corresponding hydrazones X-XII, and its nitrosation gives 1,2-dihydroimidazoquinolin-2-one (XIII).