825654-54-4

Basic information

• Product Name: 2-amino-3,6-difluorobenzoic acid
• Synonyms: 2-amino-3,6-difluorobenzoic acid;UKRORGSYN-BB BBV-237801;(2-Dimethylamino-phenyl)-acetic acid hydrochloride;3,6-difluoroanthranilic acid
• CAS NO: 825654-54-4
• Molecular Formula: C₇H₅F₂NO₂
• Molecular Weight: 173.12
• Mol File: 825654-54-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 290.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.536±0.06 g/cm3(Predicted)
• PKA: 3.67±0.10(Predicted)
• CAS DataBase Reference: 2-amino-3,6-difluorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3,6-difluorobenzoic acid(825654-54-4)
• EPA Substance Registry System: 2-amino-3,6-difluorobenzoic acid(825654-54-4)

Safety Data

• Hazardous Substances Data: 825654-54-4(Hazardous Substances Data)

Usage

General Description

2-Amino-3,6-difluorobenzoic acid, also represented by the chemical formula C7H5F2NO2, is an organic compound that belongs to the benzoic acid and derivatives class, where benzoic acid is a type of aromatic carboxylic acid. It is a white to off-white solid at room temperature. It consists of an amino group (-NH2), a carboxylic acid group (-COOH), and two fluorine atoms attached to the benzene ring, which differentiate it chemically and functionally from similar compounds. Although 2-Amino-3,6-difluorobenzoic acid is not widely researched, fluorobenzoic acids are typically used in various industrial processes and can also find applications in medicine, research, and potentially organic synthesis due to the presence of active groups that can undergo chemical reactions. Specific properties such as density, melting point, boiling point, and solubility would typically depend on its precise physical form and purity, but these are not readily available for this specific compound.

Upstream product

• 850565-99-0 N-(2,5-difluorophenyl)-2-(hydroxyimino)acetamide 
• 367-30-6 2,5-difluoroaniline 
• 749240-52-6 4,7-difluoroindoline-2,3-dione 

Relevant articles and documents

Reductive ring closure methodology toward heteroacenes bearing a dihydropyrrolo[3,2- B ]pyrrole core: Scope and limitation

A newly developed reductive ring closure methodology to heteroacenes bearing a dihydropyrrolo[3,2-b]pyrrole core was systematically studied for its scope and limitation. The methodology involves (i) the cyclization of an o-aminobenzoic acid ester derivative to give an eight-membered cyclic dilactam, and (ii) the conversion of the dilactams into the corresponding diimidoyl chloride, which undergoes (iii) reductive ring closure to install the dihydropyrrolo[3,2-b]pyrrole core. The first step of the methodology plays the key role due to its substrate limitation, which suffers from the competition of oligomerization and hydrolysis. All the dilactams could successfully convert to the corresponding diimidoyl chlorides, most of which succeeded to give the dihydropyrrolo[3,2-b]pyrrole core. The influence of the substituents and the elongation of conjugated length on the photophysical properties of the obtained heteroacenes were then investigated systematically using UV-vis spectroscopy and cyclic voltammetry. It was found that chlorination and fluorination had quite a different effect on the photophysical properties of the heteroacene, and the ring fusing pattern also had a drastic influence on the band gap of the heteroacene. The successful preparation of a series of heteroacenes bearing a dihydropyrrolo[3,2-b]pyrrole core would provide a wide variety of candidates for further fabrication of organic field-effect transistor devices.

ALKYLIDENE TETRAHYDRONAPHTHALENE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS

The invention relates to alkylidene tetrahydronaphthalene derivatives of general formula (I), to methods for their production and to their use as anti-inflammatory agents.

REARRANGED PENTANOLS, A METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS

The invention relates to compounds of formula (I), to a method for the production thereof, and to their use as antiphlogistics.