827010-09-3

Basic information

• Product Name: 2-[2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)acetylamino]benzamide
• Synonyms: 2-[2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)acetylamino]benzamide
• CAS NO: 827010-09-3
• Molecular Weight: 354.389
• Mol File: 827010-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)acetylamino]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)acetylamino]benzamide(827010-09-3)
• EPA Substance Registry System: 2-[2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanyl)acetylamino]benzamide(827010-09-3)

Safety Data

• Hazardous Substances Data: 827010-09-3(Hazardous Substances Data)

Upstream product

• 21721-78-8 2-ω-chloroacetylaminobenzamide 
• 13906-09-7 2-mercapto-3H-quinazolin-4-one 

Relevant articles and documents

Synthesis of novel 2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfinylmethyl)-3H- quinazolin-4-one

Condensation of 2-mercapto-3H-quinazolin-4-one (1) with chloroacetic acid gave 4-oxo-3,4-dihydroquinazoline-2-yl-sulfanyl)-acetic acid (2) that with anthranilamide (3) gave 2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfanylmethyl)-3H- quinazolin-4-one (4). Oxidation of 4 with sodium hypochlorite in alkaline medium gave the novel product, 2-(4-oxo-3,4-dihydroquinazolin-2-ylsulfinyl methyl)-3H-quinazolin-4-one) (5). The entire sequences of reactions in this work have been carried out using eco-friendly solvents and green conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.