828299-83-8Relevant articles and documents
Novel imidazopyrimidines-based molecules induce tetramerization of tumor pyruvate kinase M2 and exhibit potent antiproliferative profile
Patel, Sagarkumar,Globisch, Christoph,Pulugu, Priyanka,Kumar, Prasoon,Jain, Alok,Shard, Amit
, (2022/01/11)
Discovery of novel and potent lead molecules for the specific therapeutic targets by de novo drug design is still in infancy. Here, we disclose the unprecedented development of imidazopyri(mi)dine-based tumor pyruvate kinase M2 (PKM2) modulators by subseq
CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME
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Paragraph 00492, (2013/10/08)
Provided herein are carbamate compounds which may be useful in the treatment of, for example, pain, solid tumors and/or obesity.