82830-49-7 Usage
Description
1,4-Dimethoxy-2-fluorobenzene, also known as 2-Fluoro-1,4-dimethoxybenzene, is an organic compound characterized by the presence of a fluorine atom and two methoxy groups attached to a benzene ring. This unique molecular structure endows it with specific chemical properties, making it a versatile building block in various chemical reactions and applications.
Uses
Used in Organic Synthesis:
1,4-Dimethoxy-2-fluorobenzene is used as a key intermediate for the synthesis of various organic compounds. Its presence of electron-withdrawing fluorine and electron-donating methoxy groups allows for selective reactions and functional group transformations, facilitating the production of a wide range of chemical products.
Used in Pharmaceutical Industry:
1,4-Dimethoxy-2-fluorobenzene is used as a crucial raw material in the development of pharmaceuticals. Its unique structure can be incorporated into drug molecules to modulate their properties, such as solubility, stability, and bioavailability. 1,4-Dimethoxy-2-fluorobenzene plays a significant role in the synthesis of new drugs and the improvement of existing ones.
Used in Agrochemicals:
1,4-Dimethoxy-2-fluorobenzene is used as an essential component in the formulation of agrochemicals. Its chemical properties make it suitable for the development of pesticides, herbicides, and other agricultural chemicals that can effectively control pests and diseases, thereby enhancing crop productivity and quality.
Used in Dye Industry:
1,4-Dimethoxy-2-fluorobenzene is used as a vital intermediate in the production of dyes and pigments. Its structural features contribute to the color and stability of dyes, making it an indispensable component in the synthesis of various dyestuffs used in textiles, plastics, and other industries.
Check Digit Verification of cas no
The CAS Registry Mumber 82830-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,3 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 82830-49:
(7*8)+(6*2)+(5*8)+(4*3)+(3*0)+(2*4)+(1*9)=137
137 % 10 = 7
So 82830-49-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H3F5N2/c7-1-2(8)4(10)6(13-12)5(11)3(1)9/h13H,12H2
82830-49-7Relevant articles and documents
N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection
-
, (2008/06/13)
A method for treating HIV which comprises a compound of the formula STR1 wherein A is STR2 and Zi is O, Se, NRa or C(Ra)2, and Zii is --O or (=O)2 ; wherein R1, R2, R3, and R4 are as defined in the specification.
Selective, Electrophilic Fluorinations Using N-Fluoro-o-benzenedisulfonimide
Davis, Franklin A.,Han, Wei,Murphy, Christopher K.
, p. 4730 - 4737 (2007/10/02)
The synthesis of N-fluoro-o-benzenedisulfonimide (NFOBS, 2) and its use as an "electrophilic" fluorinating reagent with nucleophilic substrates is described and compared with that of N-fluorobenzenesulfonimide (NFSi, 3).NFOBS (2) is prepared in three steps in 81percent overall yield from commercially available o-benzenedisulfonic acid (4) and involves treatment of o-benzenedisulfonimide (6) with dilute fluorine (10percent F2/N2).Reaction of 2 with metal enolates, silyl enol ethers, and 1,3-dicarbonyl compounds affords the corresponding α-fluoro compounds in yields up to 95percent, with good control of mono- and difluorination.Fluorination of ortho-metalated aromatic compounds was achieved in modest to good yields (10-80percent).While the reactivities of 2 and 3 are similar, better yields were observed with the former reagent in the fluorination of metal enolates, Grignard and lithium reagents, while 3 gave better results with the ortho-lithiated aromatic substrates.The available evidence suggests an SN2-type mechanism for the fluorination of nucleophilic substrates by these reagents.
