82891-85-8Relevant articles and documents
Willgerodt–Kindler reaction-driven one pot solventless entry to 2-oxazolines
Bansal, Shivani,Gupta, Poonam,Halve
, p. 971 - 974 (2016/07/06)
We report an efficient and green protocol for the synthesis of 2-oxazolines by the reaction of aromatic nitriles with β-aminoalcohols using sulfur under solvent-free conditions. The reaction occurs via the Willgerodt-Kindler mechanism followed by transami
A mild and efficient synthesis of 2-oxazolines via transamidation- cyclodehydrosulfurisation of thioamides with 2-aminoethanol
Goud, D. Raghavender,Pathak, Uma
, p. 3678 - 3682 (2013/02/22)
Transamidation of thioamides with 2-aminoethanol, followed by cyclodehydrosulfurisation of the resultant N-(β-hydroxyethyl)thioamides, has been utilised for the mild and efficient synthesis of 2-oxazolines. The developed protocol was found to be of general applicability. Georg Thieme Verlag KG Stuttgart · New York.