828911-01-9

Basic information

• Product Name: 1-Piperazineacetamide, N-(phenylmethyl)-
• CAS NO: 828911-01-9
• Molecular Formula: C13H19N3O
• Molecular Weight: 233.313
• Mol File: 828911-01-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Piperazineacetamide, N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineacetamide, N-(phenylmethyl)-(828911-01-9)
• EPA Substance Registry System: 1-Piperazineacetamide, N-(phenylmethyl)-(828911-01-9)

Safety Data

• Hazardous Substances Data: 828911-01-9(Hazardous Substances Data)

Usage

Type

Anticonvulsant medication

Uses

Control certain types of seizures in patients with epilepsy, prevent and treat seizures during or after brain surgery, and treat certain heart rhythm disorders

Mechanism

Stabilizes electrical activity in the brain and reduces excessive and rapid firing of neurons that can lead to seizures

Side effects

Liver damage, decreased bone density, and a rare but severe allergic reaction known as Stevens-Johnson syndrome

Caution

Patients taking phenytoin should be closely monitored by a healthcare provider.

Upstream product

• 110-85-0 piperazine 
• 2564-06-9 N-benzyl-2-chloroacetamide 

Relevant articles and documents

Acetobenzylamide piperazine derivative and application thereof as cranial nerve protective agent

The invention discloses an acetobenzylamide piperazine derivative and an application thereof as a cranial nerve protective agent. Pharmacological experiments verify that the compound disclosed by the invention shows an obvious effect against glutamic acid-induced neuron exitotoxicity in vitro and obvious anti-anoxia activity in a mouse, and a herg test further shows that the compound disclosed by the invention does not have the risk of cardiotoxicity. Therefore, the compound disclosed by the invention has the advantages of being high in activity, less in side effect and good in druggability. The compound and a medicinal preparation thereof have a good curative effect for treating cranial nerve injury diseases, for example, stroke and related diseases and do not have the risk of cardiotoxicity. The acetobenzylamide piperazine derivative is a free alkali or salt of a compound with a chemical structural formula shown in the description.