82940-37-2

Basic information

• Product Name: 1,2-diphenyl-2-(phenylamino)ethanol
• Synonyms: 2-Anilino-1,2-diphenylethanol; benzeneethanol, alpha-phenyl-beta-(phenylamino)-
• CAS NO: 82940-37-2
• Molecular Formula: C₂₀H₁₉NO
• Molecular Weight: 289.371
• Mol File: 82940-37-2.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 452.4°C at 760 mmHg
• Flash Point: 128.8°C
• Density: 1.177g/cm³
• Vapor Pressure: 5.67E-09mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 1,2-diphenyl-2-(phenylamino)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diphenyl-2-(phenylamino)ethanol(82940-37-2)
• EPA Substance Registry System: 1,2-diphenyl-2-(phenylamino)ethanol(82940-37-2)

Safety Data

• Hazardous Substances Data: 82940-37-2(Hazardous Substances Data)

Usage

General Description

1,2-diphenyl-2-(phenylamino)ethanol is a chemical compound with the molecular formula C20H17NO. It is a white to light brown powder with a strong odor, and is derived from the condensation of benzophenone and aniline. 1,2-diphenyl-2-(phenylamino)ethanol is used as a reagent in organic synthesis and pharmaceutical research. It has been studied for its potential as an anti-inflammatory and antipyretic agent, and has also been investigated for its potential use in the treatment of cancer. Additionally, it has been utilized in the production of dyes, pigments, and coatings. However, due to its potential toxicity and environmental hazards, its use should be carefully controlled and monitored.

Upstream product

• 5722-91-8 1,2-diphenyl-2-(phenylamino)ethanone 
• 75-77-4 chloro-trimethyl-silane 
• 538-51-2 benzylidene phenylamine 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 1689-71-0 cis-1,2-diphenyloxirane 
• 4198-95-2 α-phenylimino-deoxybenzoin 
• 6320-11-2 α-anilino-deoxybenzoin; hydrochloride 
• 1439-07-2 trans-Stilbene oxide 
• 1689-71-0 2,3-diphenyloxirane 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 64-17-5 ethanol 
• 15833-49-5 1-2-diphenyl-2-(phenylimino) ethanol 

Downstream Products

• 99390-04-2 (5R₆S-5S₆R)-4,5,6-triphenylmorpholine-2,3-dione 
• 84327-75-3 cis-3,4,5-triphenyl-1,3-oxazolidin-2-one 
• 119-61-9 benzophenone 
• 80577-85-1 2-(4-Methoxy-phenyl)-1,5-diphenyl-1H-pyrrole-3,4-dicarboxylic acid dimethyl ester 
• 968-02-5 2,3-trans-1,2,3-triphenylaziridine 
• 84327-70-8 (4R,5R)-2-Methoxycarbonylmethyl-3,4,5-triphenyl-oxazolidine-2-carboxylic acid methyl ester 
• 84327-70-8 (4R,5S)-2-Methoxycarbonylmethyl-3,4,5-triphenyl-oxazolidine-2-carboxylic acid methyl ester 
• 84327-69-5 2,3,4,7-tetrahydro-5-methoxycarbonyl-2,3,4-triphenyl-1,4-oxazepin-7-one hemiacetal 
• 84344-87-6 2,3,4,7-tetrahydro-5-methoxycarbonyl-2,3,4-triphenyl-1,4-oxazepin-7-one 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 84327-67-3 (E)-2-[((1R,2R)-2-Hydroxy-1,2-diphenyl-ethyl)-phenyl-amino]-but-2-enedioic acid dimethyl ester 
• 84327-67-3 (Z)-2-[((1R,2R)-2-Hydroxy-1,2-diphenyl-ethyl)-phenyl-amino]-but-2-enedioic acid dimethyl ester 
• 84327-67-3 (E)-2-[((1R,2S)-2-Hydroxy-1,2-diphenyl-ethyl)-phenyl-amino]-but-2-enedioic acid dimethyl ester 
• 84327-75-3 trans-4,5-diphenyl-3-phenyloxazolin-2-one 

Relevant articles and documents

Catalytic Reductive Cross-Coupling between Aromatic Aldehydes and Arylnitriles

A reductive cross-coupling reaction between aromatic aldehydes and arylnitriles using a copper catalyst and a silylboronate as a reductant is reported. This protocol represents an unprecedented approach to the chemoselective synthesis of α-hydroxy ketones by electrophile–electrophile cross-coupling.

Reductive coupling between aromatic aldehydes and ketones or imines by copper catalysis

The copper-catalyzed reductive coupling of two different carbonyl compounds has been achieved. The reaction of aromatic aldehydes and arylketones with a silylboronate in the presence of a catalytic amount of a CuCl-N-heterocyclic carbene (NHC) complex and a stoichiometric amount of alkoxide base yielded cross-coupled 1,2-diol derivatives. A reaction pathway is proposed that involves the catalytic formation of a nucleophilic α-silyloxybenzylcopper(I) species from the aromatic aldehyde and its subsequent coupling with the arylketone. This process was amenable to asymmetric catalysis. This copper catalyst system also enabled the reductive coupling between aromatic aldehydes and imines.

Fe(OH)3 nano solid material: An efficient catalyst for regioselective ring opening of aryloxy epoxide with amines under solvent free condition

Iron hydroxide-Fe(OH)3and iron oxides (Fe3O4and Fe2O3) were successfully prepared and characterized. These materials were employed as efficient and environmentally benign heterogeneous catalysts for t