82978-68-5 Usage
Chemical structure
A complex molecule with a long chain of carbon atoms, including functional groups such as amino, carboxylic acid, and carbonyl.
Octahydro-1H-indole ring system
The structure contains an octahydro-1H-indole ring system with a carboxylic acid group attached at one end.
Ethoxycarbonyl group
The compound also contains an ethoxycarbonyl group, which is a type of ester functional group.
Potential applications
Likely has applications in the pharmaceutical and chemical industries due to its complex structure and potential biological activities.
Biological activities
The exact properties and potential uses may vary, but the compound's complex structure suggests it could have biological activities.
Ester functional group
The presence of an ethoxycarbonyl group indicates the compound has ester functional group properties, which can be involved in various chemical reactions and interactions.
Amino and carboxylic acid functional groups
The compound's structure includes amino and carboxylic acid functional groups, which can participate in reactions such as hydrogen bonding and amide formation.
Hydrophobic and hydrophilic regions
The long carbon chain and ethoxycarbonyl group contribute to the compound's hydrophobic properties, while the carboxylic acid group provides hydrophilic characteristics.
Solubility
The compound's solubility may vary depending on the solvent used, with potential solubility in polar solvents due to the presence of the carboxylic acid group.
Reactivity
The compound may exhibit reactivity with other molecules, particularly those that can interact with its functional groups, such as nucleophiles, electrophiles, and acids or bases.
Check Digit Verification of cas no
The CAS Registry Mumber 82978-68-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,9,7 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 82978-68:
(7*8)+(6*2)+(5*9)+(4*7)+(3*8)+(2*6)+(1*8)=185
185 % 10 = 5
So 82978-68-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)
82978-68-5Relevant articles and documents
Method for preparing perindopril despinner and intermediate thereof
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Paragraph 0038; 0057-0059, (2018/11/22)
The invention discloses a method for preparing perindopril despinner and an intermediate thereof. The method comprises the following steps: halogenating N-propionyl indole-2-carboxylic acid under theaction of a halogenation reagent so as to obtain a halogenation product, and further carrying out amine substitution and catalytic hydrogenation reduction on the obtained halogenation product, therebyobtaining the perindopril despinner. Compared with the prior art, the method is cheap and easy in reaction raw material, has a total yield as high as 64%, is high in product purity and is applicableto industrial production.
PROCESS FOR THE PREPARATION OF THE L-ARGININE SALT OF PERINDOPRIL
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Paragraph 0047, (2013/07/19)
Process for the preparation of the compound of formula (I):
PROCESS FOR THE PREPARATION OF PERINDOPRIL ERBUMINE SALT AND NOVEL POLYMORPH (S) THEREOF
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Page/Page column 12, (2008/12/07)
A single pot process for the preparation of perindopril erbumine salt according to which condensation of (2S, 3aS, 7aS)-octahydroindole-2-carboxylic acid benzyl ester para toluene sulfonate with N-((S-)-ethoxy carbonyl -1-ethyl-(S)-alanine, catalytic hydrogenation of benzyl ester of (2S, 3aS, 7aS)-1-{2-[1-(ethoxycarbonyl)-(S)-butylamino]-(S)propionyl}- octahydro-indole-2-carboxylate and conversion of (2S,3aS, 7aS)-1-{2-[1-ethoxycarbonyl)_(S)-butylamino]-(S)-propionyl}octahydroindole-2-carboxylic acid to its perindopril erbumine salt are carried out in a single pot using a single solvent such as isopropyl acetate to obtain perindopril erbumine salt of very high purity. Also a novel polymorph S of perindopril erbumine having X-ray diffraction peaks of 9.10, 14.64, 15.37, 16.58, 17.39, 19.99, 20.62, 21.50, 22.15, 22.60, 24.20, 27.55 ± 0.2 at 2Θ values. Also processes for preparing the novel polymorph S.
