83015-33-2

Basic information

• Product Name: (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene
• Synonyms: (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene
• CAS NO: 83015-33-2
• Molecular Weight: 289.091
• Mol File: 83015-33-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene(83015-33-2)
• EPA Substance Registry System: (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene(83015-33-2)

Safety Data

• Hazardous Substances Data: 83015-33-2(Hazardous Substances Data)

Usage

Description

(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is a clear, colorless liquid that is an organofluorine compound containing a benzene ring and a tetrafluoroethylsulfanyl group, with a bromine atom attached to the benzene ring. It is commonly used in organic synthesis and chemical research.
Used in Pharmaceutical Industry:
(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is used as an intermediate in the production of pharmaceuticals for its unique properties and reactivity.
Used in Agrochemical Industry:
(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is used as a building block in the synthesis of agrochemicals to develop new and effective products for agricultural applications.
Used in Material Science:
(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is used as a component in the development of materials such as surfactants and polymers due to its organofluorine nature and reactivity.
Used in Electronics Industry:
(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is used in the manufacturing of electronic components, taking advantage of its chemical properties for specific applications.
Used as a Reagent in Chemical Reactions:
(2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene is used as a reagent in various chemical reactions for its ability to participate in a range of organic synthesis processes.
Safety Note:
It is important to handle and store (2-bromo-1,1,2,2-tetrafluoroethylsulfanyl)benzene with caution, as it may be harmful if inhaled, swallowed, or absorbed through the skin, and it can also cause irritation to the eyes and respiratory system.

Upstream product

• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 108-98-5 thiophenol 

Downstream Products

• 1000293-91-3 trimethyl(1,1,2,2-tetrafluoro-2-(phenylsulfanyl)ethyl)silane 
• 1333419-02-5 1,1,1,3,3,4,4-heptafluoro-2-phenyl-4-(phenylthio)butan-2-ol 
• 1333419-08-1 (3-(allyloxy)-1,1,2,2-tetrafluoro-3-phenylpropyl)(phenyl)sulfane 
• 1333419-09-2 (3-(allyloxy)-1,1,2,2-tetrafluoro-3-(4-chlorophenyl)propyl)(phenyl)sulfane 
• 1333418-94-2 2,2,3,3-tetrafluoro-1-phenyl-3-(phenylthio)propan-1-ol 
• 1333419-10-5 (3-(allyloxy)-1,1,2,2-tetrafluoro-3-(4-methoxyphenyl)propyl)(phenyl)sulfane 
• 1333419-11-6 (3-(allyloxy)-1,1,2,2-tetrafluoro-3-(naphthalen-2-yl)propyl)(phenyl)sulfane 
• 1333419-12-7 (3-(allyloxy)-1,1,2,2-tetrafluorononyl)(phenyl)sulfane 
• 1333419-13-8 (3-(allyloxy)-1,1,2,2-tetrafluoro-5-phenylpentyl)(phenyl)sulfane 
• 1333419-14-9 (E)-(3-(cinnamyloxy)-1,1,2,2-tetrafluoro-3-phenylpropyl)(phenyl)sulfane 
• 1333418-95-3 2,2,3,3-tetrafluoro-1-(4-chlorophenyl)-3-(phenylthio)propan-1-ol 
• 1333418-96-4 2,2,3,3-tetrafluoro-1-(4-methoxyphenyl)-3-(phenylthio)propan-1-ol 
• 1333418-97-5 2,2,3,3-tetrafluoro-1-(naphthalen-1-yl)-3-(phenylthio)propan-1-ol 
• 1333418-98-6 2,2,3,3-tetrafluoro-1-(naphthalen-2-yl)-3-(phenylthio)propan-1-ol 

Relevant articles and documents

Selective fluoroalkylation of thiophenols by 1,2-dibromotetrafluoroethane activated by sulfur dioxide

Treatment of 1,2-dibromotetrafluoroethane with thiophenols in DMF in the presence of sulfur dioxide and pyridines having pKa > 5 gives fluoroalkylated thioethers in high yields under mild conditions. The influence of thiophenol reactant structu

Expanding the Scope of Hypervalent Iodine Reagents for Perfluoroalkylation: From Trifluoromethyl to Functionalized Perfluoroethyl

A series of new hypervalent iodine reagents based on the 1,3-dihydro-3,3-dimethyl-1,2-benziodoxole and 1,2-benziodoxol-3-(1H)-one scaffolds, which contain a functionalized tetrafluoroethyl group, have been prepared, characterized, and used in synthetic applications. Their corresponding electrophilic fluoroalkylation reactions with various sulfur, oxygen, phosphorus, and carbon-centered nucleophiles afford products that feature a tetrafluoroethylene unit, which connects two functional moieties. A related λ3-iodane that contains a fluorophore was shown to react with a cysteine derivative under mild conditions to give a thiol-tagged product that is stable in the presence of excess thiol. Therefore, these new reagents show a significant potential for applications in chemical biology as tools for fast, irreversible, and selective thiol bioconjugation.

Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species

We have made a systematic investigation on the copper(0)-mediated tetrafluoroethylenation of iodobenzene with structurally diverse 2-bromo-1,1,2,2-tetrafluoroethyl compounds. A comparison of this reaction with 1,2,2-trifluoro-1-phenylethylation and the known functionalized difluoroalkylation demonstrates that the substituent R of α,α-difluoroalkyl copper species RCF2Cu plays a crucial role on their reactivity, which is believed to be useful for the development of new fluoroalkylation reactions under the promotion of transition metals.