83026-93-1

Basic information

• Product Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-phenyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• Synonyms: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-phenyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• CAS NO: 83026-93-1
• Molecular Weight: 454.439
• Mol File: 83026-93-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-phenyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-phenyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(83026-93-1)
• EPA Substance Registry System: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-phenyl-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(83026-93-1)

Safety Data

• Hazardous Substances Data: 83026-93-1(Hazardous Substances Data)

Upstream product

• 5987-74-6 6-iodo-9-[β-(2',3',5'-tri-O-acetyl)-D-ribofuranosyl]purine 
• 71-43-2 benzene 
• 591-50-4 iodobenzene 
• 58-61-7 adenosine 
• 5987-73-5 2',3',5'-O-triacetyl-6-chloroinosine 
• 100-58-3 phenylmagnesium bromide 
• 2004-06-0 6-Chloropurine riboside 
• 15981-63-2 2',3',5'-tri-O-acetylnebularine 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 7387-57-7 triacetyladenosine 

Downstream Products

• 1310063-73-0 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(2-acetoxyphenyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 1310063-74-1 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(2,6-diacetoxyphenyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 1284287-16-6 6-([1,1'-biphenyl]-2-yl)-9-β-D-(2',3',5'-tri-O-acetyl)ribofuranosyl-9H-purine 
• 1416131-65-1 C₁₈H₂₁N₄O₇P 
• 1416131-66-2 C₃₉H₄₁N₈O₁₀P 
• 1379667-45-4 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-[6-{2-(4-methylphenylsulfonamido)phenyl}-9H-purin-9-yl]tetrahydrofuran-3,4-diyl diacetate 
• 84765-98-0 6-phenyl-9-(β-D-ribofuranosyl)-9H-purine 

Relevant articles and documents

PdII-Catalyzed Purine-Directed Ortho Nitration of 6-Arylpurines by C(sp2)–H Activation: A Practical Approach to Synthesize 6-(2-Nitroaryl)-Purine Derivatives

Herein we report a method for PdII-catalyzed purine-directed ortho nitration of 6-arylpurines via C(sp2)–H activation by using tBuONO/O2 as nitration agent. This procedure is highly efficient and produces a range of 6-(2-nitroaryl)-purine derivatives with good chemoselectivity and functional-group tolerance. The utility of the method is further illustrated in the synthesis of antibacterial agent.

Indole- and Pyrrole-BX: Bench-Stable Hypervalent Iodine Reagents for Heterocycle Umpolung

The one-step synthesis of the bench-stable hypervalent iodine reagents IndoleBX and PyrroleBX using mild Lewis acid catalyzed conditions is reported. The new reagents are stable up to 150 °C and were applied in the C?H arylation of unactivated arenes using either rhodium or ruthenium catalysts. A broad range of heterocyclic systems of high interest for synthetic and medicinal chemistry was accessed in high yields. The developed C?H functionalization could not be achieved using reported reagents or methods, highlighting the unique reactivity of Indole- and Pyrrole-BX.

Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: Palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides [1]

A series of C-6 alkyl, cycloalkyl, and aryl-9-(β-d-ribofuranosyl) purines were synthesized and their substrate activities with Escherichia coli purine nucleoside phosphorylase (E. coli PNP) were evaluated. (Ph 3P)4Pd-mediated cross-c