83053-82-1Relevant articles and documents
Formation of a novel ring system : An unexpected intermolecular cyclization
Kumar, G. Biju,Shah, Amrish C.,Pilati, Tullio
, p. 3297 - 3300 (1997)
A novel chiral ten membered heterocyclic ring is synthesised in two steps from phthalimide derivatives of (R) and (S) -2-amino-1-butanol. The structures have been unambiguously established by single crystal X-ray diffraction of one of the compounds.
Synthesis of phenyl and substituted phenyl 3-ethyl-2,3,5,9b-tetrahydro[1,3]oxazolo[2,3-a]isoindol-5-ones
Naira, Dinesh S.,Pauranik, Vedavati,Shaha, Amrish C.
, p. 772 - 774 (2007/10/03)
Addition of various aryl magnesium bromides to (R) or (S)-2-(1-hydroxybutyl)phthalimide results in the formation of substituted (R) or (S)-3-hydroxy-2(1-hydroxybutyl)isoindol-1-ones which are subsequently cyclised under highly acidic conditions to give the title compounds in moderate yields.