831217-01-7

Basic information

• Product Name: Acetildenafil
• Synonyms: 5-[2-Ethoxy-5-[2-(4-ethyl-1-piperazinyl)acetyl]phenyl]-1,6-dihydro-1-methyl -3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;Acetildenafil;Hongdenafil;7H-Pyrazolo[4,3-d]pyriMidin-7-one, 5-[2-ethoxy-5-[2-(4-ethyl-1-piperazinyl)acetyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-;Acetildenafil (Hongdenafil);5-[2-Ethoxy-5-[2-(4-ethyl-piperazin-1-yl)-acetyl]-phenyl]-1-Methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyriMidin-7-one;5-[2-ethoxy-5-[2-(4-ethylpiperazin-1-yl)acetyl]phenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
• CAS NO: 831217-01-7
• Molecular Formula: C25H34N6O3
• Molecular Weight: 466.583
• EINECS: 202-303-5
• Product Categories: All Inhibitors;Bases & Related Reagents;Inhibitors;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 831217-01-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 131-133°C
• Boiling Point: 656.7±65.0 °C(Predicted)
• Appearance: off-white to pale yelow solid
• Density: 1.28 g/cm³
• Refractive Index: 1.637
• Storage Temp.: Refrigerator
• Solubility: Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)
• PKA: 7.61±0.10(Predicted)
• CAS DataBase Reference: Acetildenafil(CAS DataBase Reference)
• NIST Chemistry Reference: Acetildenafil(831217-01-7)
• EPA Substance Registry System: Acetildenafil(831217-01-7)

Safety Data

• Hazardous Substances Data: 831217-01-7(Hazardous Substances Data)

Usage

Description

Acetildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil, characterized by its off-white to pale yellow solid appearance. It is a synthetic compound designed to mimic the effects of sildenafil, which is commonly used for treating erectile dysfunction and pulmonary arterial hypertension.

Uses

Used in Pharmaceutical Industry:
Acetildenafil is used as a PDE5 inhibitor for the treatment of erectile dysfunction. It works by increasing blood flow to the penis, allowing for an erection to occur when sexually stimulated. This helps men with erectile dysfunction to achieve and maintain an erection.
Additionally, Acetildenafil may be used as a research chemical for studying the effects of PDE5 inhibitors on various physiological processes, including blood flow regulation and potential applications in other medical conditions.

InChI:InChI=1/C25H34N6O3/c1-5-8-19-22-23(29(4)28-19)25(33)27-24(26-22)18-15-17(9-10-21(18)34-7-3)20(32)16-31-13-11-30(6-2)12-14-31/h9-10,15H,5-8,11-14,16H2,1-4H3,(H,26,27,33)