83128-58-9Relevant articles and documents
Derivatives of Barbituric Acid, XXX: Synthesis of Racemic and Optically Active Barbituric Acids Carrying Basic Substituents
Knabe, Joachim,Reinhardt, Joerg
, p. 706 - 716 (1982)
Monoalkylated malonates were condensed with N-monosubstituted ureas to yield the 5-monosubstituted barbituric acids 1, which were reacted to the 5-bromobarbituric acids 2.From 2 the barbituric acids 3-5 having basic substituents were obtained by nucleophi