83256-53-5Relevant articles and documents
INTRAMOLECULAR CYCLIZATION OF N-PHTHALYL-β-ARYL-β-ALANINE PHENYLHYDRAZIDE
Portnov, Yu. N.,Zabrodnyaya, V. G.,Voronin, V. G.,Kost, A. N.
, p. 703 - 706 (2007/10/02)
The reaction of N-phthalyl-β-aryl-β-alanine N'-methyl-N'-phenylhydrazides with phosphorus oxychloride (at cca 80 deg C) is accompanied by further transformations of the initially formed 2-aminoindole derivatives and leads to isoindolopyrimidoindole derivatives.Intermediate 2-aminoindoles were isolated at lower reaction temperatures.The hydrolysis of the isoindolopyrimidoindole derivatives was studied.The structures of the compounds obtained were established on the basis of the PMR, IR, and UV spectra and the results of elementary analysis.