832714-37-1

Basic information

• Product Name: 1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinol
• Synonyms: 1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinol;4-Hydroxy-1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidine
• CAS NO: 832714-37-1
• Molecular Formula: C₁₀H₁₇N₃O₂
• Molecular Weight: 211.26088
• Mol File: 832714-37-1.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• Density: 1.186
• CAS DataBase Reference: 1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinol(832714-37-1)
• EPA Substance Registry System: 1-[3-(1-Methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinol(832714-37-1)

Safety Data

• Hazardous Substances Data: 832714-37-1(Hazardous Substances Data)

Usage

Synonyms

YJ-162043

Structure

Contains a piperidinol ring and an oxadiazolyl ring

Potential Pharmaceutical Properties

a. Anti-inflammatory agent
b. Analgesic agent

Potential Applications

a. Treatment of inflammation and pain
b. Calcium channel blocker
c. Treatment of cardiovascular conditions

Research Status

Further research needed to fully understand its biological and pharmaceutical properties and potential applications in medicine.

Upstream product

• 51075-37-7 4-hydroxypiperidine-1-carbonitrile 
• 849833-56-3 N'-hydroxy-2-methylpropanimidamide 
• 35613-84-4 isobutyramide oxime 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 871681-75-3 O-amidinoamidoxime 
• 849833-56-3 N-hydroxyisobutyramidine 

Downstream Products

• 1001397-63-2 2,5-difluoro-4-[4-({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}oxy)-5,6-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]benzonitrile 
• 1001397-67-6 7-(4-bromo-2,5-difluorophenyl)-4-({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}oxy)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 
• 1001397-57-4 7-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-4-({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}oxy)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 
• 1190364-39-6 1-(4-(methylsulfonyl)phenyl)ethanone O-6-(1-(3-iso-propyl-1,2,4-oxadiazol-5-yl)piperidin-4-yloxy)-5-methylpyrimidin-4-yl oxime 
• 1001397-64-3 7-[2-fluoro-4-(methylsulfonyl)phenyl]-4-({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}oxy)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 
• 1384951-03-4 7-(2-fluoro-4-methanesulfonylphenyl)-4-[1-(3-isopropyl[1,2,4]oxadiazol-5-yl)piperidin-4-yloxy]thieno[3,2-d]pyrimidine 
• 1384951-39-6 5-(4-(7-(2-chloro-4-methoxyphenyl)thieno[3,2-d]pyrimidin-4-yloxy)piperidin-1-yl)-3-isopropyl-1,2,4-oxadiazole 
• 1258604-37-3 2-(4-(6-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yloxy)-5-methylpyrimidin-4-yloxy)phenyl)propane-1,3-diol 
• 1258604-36-2 5-(4-(6-(4-(2,2-dimethyl-1,3-dioxan-5-yl)phenoxy)-5-methylpyrimidin-4-yloxy)piperidin-1-yl)-3-isopropyl-1,2,4-oxadiazole 
• 1351338-67-4 (3R,4S)-4-(2,5-difluorophenyl)-1-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-yl)piperidin-4-yloxymethyl]pyrimidin-2-yl}pyrrolidin-3-ylamine 
• 1351343-66-2 [(3R,4S)-4-(2,5-difluoro-phenyl)-1-(5-{(S)-1-[1-(4-methyl-thiazol-2-yl)piperidin-4-yl]ethoxy}pyrimidin-2-yl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 1351343-64-0 [(3R,4S)-4-(2,5-difluoro-phenyl)-1-(5-{(S)-1-[1-(N-hydroxycarbamimidoyl)piperidin-4-yl]ethoxy}pyrimidin-2-yl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 1351343-50-4 [(3R,4S)-1-{5-[(S)-1-(1-cyano-piperidin-4-yl)ethoxy]pyrimidin-2-yl}-4-(2,5-difluoro-phenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 1351343-49-1 {(3R,4S)-4-(2,5-difluoro-phenyl)-1-[5-((S)-1-piperidin-4-yl-ethoxy)pyrimidin-2-yl]pyrrolidin-3-yl}carbamic acid tert-butyl ester 

Relevant articles and documents

NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The present invention relates to compounds of general formula I, wherein R1, LP, HetAr, Ar, and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.

NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS

The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.

NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS

The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.