83278-86-8

Basic information

• Product Name: 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL
• Synonyms: 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL;2-HYDROXYMETHYLCHROMANE;Chroman-2-yl-methanol;2-(Hydroxymethyl)chroman 97%;(3,4-Dihydro-2H-chromen-2-yl)methanol, (3,4-Dihydro-2H-1-benzopyran-2-yl)methanol;3,4-dihydro-2H-1-benzopyran-2-ylMethanol;2-(Hydroxymethyl)chroman97%
• CAS NO: 83278-86-8
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Product Categories: Hydroxymethyl's;Fused Ring Systems
• Mol File: 83278-86-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 44 °C
• Boiling Point: 293.2 °C at 760 mmHg
• Flash Point: 133.9 °C
• Appearance: /
• Density: 1.125 g/cm³
• Storage Temp.: 2-8°C
• PKA: 14.18±0.10(Predicted)
• CAS DataBase Reference: 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL(83278-86-8)
• EPA Substance Registry System: 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL(83278-86-8)

Safety Data

• Hazardous Substances Data: 83278-86-8(Hazardous Substances Data)

Usage

General Description

3,4-Dihydro-2H-chromen-2-ylmethanol is a chemical compound with a molecular formula C10H12O2. It is a type of chromene derivative that contains a chroman ring system. 3,4-DIHYDRO-2H-CHROMEN-2-YLMETHANOL has potential pharmaceutical applications, particularly in the development of new drugs for various purposes. It may exhibit antioxidant, anti-inflammatory, and antifungal properties, making it a target for further research and development. Its unique chemical structure and potential biological activities make it an interesting compound for the scientific community to explore and potentially harness for various medical and industrial applications.

Upstream product

• 51939-71-0 chroman-2-carboxylic acid 
• 24698-77-9 ethyl Chroman-2-carboxylate 
• 543-27-1 isobutyl chloroformate 
• 4940-39-0 acide chromone carboxylique-2 
• 66598-81-0 chroman-2-carboxylic acid methyl ester 
• 83780-47-6 (-)-(R)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 
• 694-80-4 2-bromo-1-chlorobenzene 
• 59363-19-8 4-(2-Chloro-phenyl)-butane-1,2-diol 

Downstream Products

• 99290-94-5 1-Chroman-2-ylmethyl-piperidine 
• 104605-88-1 3,4-dihydro-2H-1-benzopyran-2-methanol 4-methylbenzenesulfonate (ester) 

Relevant articles and documents

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

SULFAMATE AND SULFAMIDE DERIVATIVES FOR THE TREATMENT OF EPILEPSY AND RELATED DISORDERS

The present invention is directed to novel sulfamide and sulfamate derivatives, pharmaceutical composlons containing them and their use in the treatment of epilepsy and related disorders.

A highly efficient enantioselective synthesis of 2-methyl chromans via four sequential palladium-catalyzed reactions

An enantioselective synthesis of substituted 2-methyl chromans was accomplished in four steps using four sequential Pd-catalyzed reactions. A study of the key palladium-catalyzed regioselective aryl ether ring formation of two different substrates was also carried out to better understand the factors which affect the selectivity of the reaction.