833-39-6

Basic information

• Product Name: Benzenemethanol, 4-hydroxy-a-phenyl-
• CAS NO: 833-39-6
• Molecular Formula: C13H12O2
• Molecular Weight: 200.237
• Mol File: 833-39-6.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-hydroxy-a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-hydroxy-a-phenyl-(833-39-6)
• EPA Substance Registry System: Benzenemethanol, 4-hydroxy-a-phenyl-(833-39-6)

Safety Data

• Hazardous Substances Data: 833-39-6(Hazardous Substances Data)

Upstream product

• 1137-42-4 4-Hydroxybenzophenone 
• 89899-44-5 (3-bromo-4-hydroxyphenyl)(phenyl)methanone 
• 92434-59-8 4-Acetoxy-benzhydrylbromid 
• 54589-41-2 (4-(benzyloxy)phenyl)(phenyl)methanone 
• 7732-18-5 water 
• 64-17-5 ethanol 
• 7647-01-0 hydrogenchloride 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 934-56-5 trimethyl(phenyl)stannane 
• 123-08-0 4-hydroxy-benzaldehyde 
• 61365-71-7 p-quinone α-phenylmethide 
• 106-41-2 4-bromo-phenol 
• 540-38-5 p-Iodophenol 

Downstream Products

• 2150-58-5 phenol blue 
• 100-52-7 benzaldehyde 
• 1435-60-5 4-(4'-hydroxyphenylazo)nitrobenzene 
• 955-37-3 3,5-dibromo-4-hydroxy-benzhydrol 
• 118-79-6 2,4,6-tribromophenol 
• 1172130-64-1 C₁₅H₁₂O₄ 
• 1172130-61-8 C₁₉H₂₀O₄ 
• 233584-35-5 C₁₇H₁₆O₄ 
• 1172130-62-9 C₂₁H₂₄O₄ 
• 948044-25-5 ACA-28 
• 1172130-63-0 C₁₉H₁₆O₄ 
• 101-53-1 p-benzylphenol 
• 1186642-08-9 4-(1-phenylbut-3-en-1-yl)phenol 

Relevant articles and documents

Discovery of new benzhydrol biscarbonate esters as potent and selective apoptosis inducers of human melanomas bearing the activated ERK pathway: SAR studies on an ERK MAPK signaling modulator, ACA-28

The recent discovery that an ERK signaling modulator [ACA-28 (2a)] preferentially kills human melanoma cell lines by inducing ERK-dependent apoptosis has generated significant interest in the field of anti-cancer therapy. In the first SAR study on 2a, here, we successfully developed candidates (2b, 2c) both of which induce more potent and selective apoptosis towards ERK-active melanoma cells than 2a, thus revealing the structural basis for inducing the ERK-dependent apoptosis and proposing the therapeutic prospect of these candidates against ERK-dependent cancers represented by melanoma.

Chiral phosphoric acid catalyzed asymmetric addition of naphthols to para -quinone methides

An asymmetric addition of naphthols to in situ generated para-quinone methides catalyzed by a chiral phosphoric acid is described. A range of useful triarylmethanes can be generated from stable general para-hydroxybenzyl alcohols with good efficiency and enantioselectivity.

Br?nsted Acid-Catalyzed Reactions of Trifluoroborate Salts with Benzhydryl Alcohols

Br?nsted acid-catalyzed carbon-carbon bond forming methodology using potassium alkynyl- and alkenyltrifluoroborate salts has been developed. Organotrifluoroborates react with benzhydryl alcohols to afford a broad range of alkynes and alkenes in good to excellent yields. This protocol features good atom economy because organotrifluoroborate salts and alcohols react in a 1:1 ratio. Furthermore, a variety of unprotected functional groups were tolerated under the developed conditions, including amide, aldehyde, free hydroxyl, and carboxylic acid.