83375-05-7

Basic information

• Product Name: p-chlorobenzhydrylurea
• Synonyms: p-chlorobenzhydrylurea
• CAS NO: 83375-05-7
• Molecular Weight: 260.723
• Mol File: 83375-05-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-chlorobenzhydrylurea(CAS DataBase Reference)
• NIST Chemistry Reference: p-chlorobenzhydrylurea(83375-05-7)
• EPA Substance Registry System: p-chlorobenzhydrylurea(83375-05-7)

Safety Data

• Hazardous Substances Data: 83375-05-7(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 106-39-8 bromochlorobenzene 
• 108-86-1 bromobenzene 
• 56542-87-1 1-(4-chlorophenyl)-N-(diphenylmethylene)methanamine 
• 7699-79-8 benzhydrylidene-benzyl-amine 
• 5267-39-0 4-chlorobenzhydrylamine hydrochloride 
• 57-13-6 urea 
• 590-28-3 potassium cyanate 
• 28022-43-7 p-chlorobenzhydrylamine 

Downstream Products

• 160807-85-2 1,3-bis((4-chlorophenyl)(phenyl)methyl)urea 

Relevant articles and documents

Synthesis of diarylmethylamines via palladium-catalyzed regioselective arylation of 1,1,3-triaryl-2-azaallyl anions

Diarylmethylamines are of great interest due to their prevalence in pharmaceutical chemistry. As a result, new methods for their synthesis are in demand. Herein, we report a versatile protocol for the synthesis of diarylmethylamine derivatives involving palladium-catalyzed arylation of in situ generated 2-azaallyl anion intermediates. The 2-azaallyl anions are generated by reversible deprotonation of readily available aldimine and ketimine precursors. Importantly, the arylated aldimine and ketimine products do not undergo isomerization under the reaction conditions. Scale-up of the arylation and hydrolysis of the resulting products to furnish diarylmethylamines were also successfully performed. This journal is the Partner Organisations 2014.

Phytotoxic activity 4-chlorobenzylamine derivatives

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