83511-07-3 Usage
Description
3,7-Dihydroxy-2-naphthoic acid is an organic compound characterized by the presence of two hydroxyl groups at the 3rd and 7th positions and a carboxylic acid group at the 2nd position on a naphthalene ring. It is a key intermediate in the synthesis of various chemical compounds and has potential applications in pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
3,7-Dihydroxy-2-naphthoic acid is used as a substrate for the enzyme NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. This enzyme catalyzes the O-methylation of 2,7-dihydroxy-5-methyl-1-naphthoic acid, which is an important step in the production of neocarzinostatin, a potent antitumor agent.
Used in Chemical Synthesis:
3,7-Dihydroxy-2-naphthoic acid is used as a starting material in the synthesis of 3-hydroxy-7-methoxy-2-naphthoic acid, which can be further utilized in the development of various chemical compounds and pharmaceuticals. Its unique structure and functional groups make it a versatile building block for organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 83511-07-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,1 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 83511-07:
(7*8)+(6*3)+(5*5)+(4*1)+(3*1)+(2*0)+(1*7)=113
113 % 10 = 3
So 83511-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8O4/c12-8-2-1-6-5-10(13)9(11(14)15)4-7(6)3-8/h1-5,12-13H,(H,14,15)
83511-07-3Relevant articles and documents
Biocatalytic synthesis of dihydroxynaphthoic acids by cytochrome P450 CYP199A2
Furuya, Toshiki,Kino, Kuniki
experimental part, p. 2797 - 2799 (2010/09/17)
CYP199A2, a bacterial P450 monooxygenase from Rhodopseudomonas palustris, was found to exhibit oxidation activity towards three hydroxynaphthoic acids. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 efficiently catalyzed the re
1,8,17,24-Tetraoxa(2,6)naphthalenophane-3,5,19,21-tetrayne-10,13-dicarboxylic Acid Derivatives, Novel Complexors of Aromatic Guests
Jarvi, Esa T.,Whitlock, Howard W.
, p. 7196 - 7204 (2007/10/02)
Synthesis and complexation behavior of the title molecules are described.Study of aromatic solvent induced shifts of these molecules support the contention that their large cavity can accomodate aromatic rings.The behavior of acid 1a in water suggests that this effect enhanced in aqueous medium, as is expected for formation of hydrophobic inclusion complexes.In contrast to the rigid naphthalenophanes (1), their saturated derivatives (7) exist in a collapsed conformation and do not incorporate aromatic guests.