835633-83-5

Basic information

• Product Name: 5-Pyrimidinecarboxamide, 2,4-dichloro-N-(2,6-dichlorophenyl)-
• CAS NO: 835633-83-5
• Molecular Formula: C11H5Cl4N3O
• Molecular Weight: 336.992
• Mol File: 835633-83-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxamide, 2,4-dichloro-N-(2,6-dichlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxamide, 2,4-dichloro-N-(2,6-dichlorophenyl)-(835633-83-5)
• EPA Substance Registry System: 5-Pyrimidinecarboxamide, 2,4-dichloro-N-(2,6-dichlorophenyl)-(835633-83-5)

Safety Data

• Hazardous Substances Data: 835633-83-5(Hazardous Substances Data)

Upstream product

• 23945-44-0 2,4-dihydroxypyrimidine-5-carboxylic acid 
• 37131-89-8 2,4-dichloropyrimidine-5-carboxylic acid 
• 608-31-1 2,6-Dichloroaniline 
• 2972-52-3 2,4-dichloropyrimidine-5-carbonyl chloride 

Downstream Products

• 927681-16-1 tert-butyl 4-(2-(2-chloro-5-((2,6-dichlorophenyl)carbamoyl)pyrimidin-4-ylhydrazinyl)ethyl)piperidine-1-carboxylate 
• 927681-13-8 4-(1-(but-3-enyl)hydrazinyl)-2-chloro-N-(2,6-dichlorophenyl)pyrimidine-5-carboxamide 
• 1099657-52-9 C₁₈H₂₁Cl₃N₆O₂ 
• 1099657-56-3 C₁₈H₂₁Cl₃N₆O₂ 
• 1099657-58-5 C₁₉H₂₄Cl₃N₇O 
• 1099657-34-7 C₁₇H₂₀Cl₃N₅O₂ 
• 1099657-60-9 C₁₅H₁₇Cl₃N₆O 
• 1099657-50-7 C₁₈H₂₂Cl₃N₇O 

Relevant articles and documents

PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT

The present invention relates to a pyrazolopyrimidine derivative, a preparation method thereof and a pharmaceutical composition comprising the same as an active ingredient for the prevention or treatment of cancer, autoimmune disease and brain disease. The pyrazolopyrimidine derivative of the present invention exhibits excellent Bruton's tyrosine kinase inhibition activity, so that it can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer, autoimmune disease and Parkinson's disease.

2-AMINO-4-HYDROXY-5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF T CELL ACTIVATION FOR THE TREATMENT OF INFLAMMATORY DISEASES

The present invention relates to pyrimidine or pyridine carboxamides or pharmaceutically-acceptable salts thereof. Also included is a method of treatment of inflammation, inhibition of T cell activation and proliferation, arthritis, rheumatoid arthritis,