835929-66-3Relevant articles and documents
Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide
Smith III, Amos B.,Freeze, B. Scott,LaMarche, Matthew J.,Hirose, Tomoyasu,Brouard, Ignacio,Rucker, Paul V.,Xian, Ming,Sundermann, Kurt F.,Shaw, Simon J.,Burlingame, Mark A.,Horwitz, Susan Band,Myles, David C.
, p. 311 - 314 (2007/10/03)
(Chemical Equation Presented) The design, syntheses, and biological evaluation of 22 totally synthetic analogues of the potent microtubule- stabilizing agent (+)-discodermolide (1) have been achieved. Structure-activity relationships of the C(19) carbamat