83873-16-9

Basic information

• Product Name: Epoxy Metradiene
• Synonyms: Epoxy Metradiene
• CAS NO: 83873-16-9
• Molecular Formula: C₂₂H₂₈O₄
• Molecular Weight: 356.45532
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 83873-16-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 183 °C
• Boiling Point: 522.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• PKA: 12.94±0.70(Predicted)
• CAS DataBase Reference: Epoxy Metradiene(CAS DataBase Reference)
• NIST Chemistry Reference: Epoxy Metradiene(83873-16-9)
• EPA Substance Registry System: Epoxy Metradiene(83873-16-9)

Safety Data

• Hazardous Substances Data: 83873-16-9(Hazardous Substances Data)

Usage

Description

Epoxy Metradiene, also known as F593145 impurity, is a chemical compound derived from the synthesis of Fluorometholone, a glucocorticoid with anti-inflammatory properties. It is characterized by its unique chemical structure and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
Epoxy Metradiene is used as an impurity in the synthesis of Fluorometholone, a glucocorticoid with anti-inflammatory properties. It plays a crucial role in the development and production of this medication, which is used to treat various inflammatory conditions.
Used in Research and Development:
Epoxy Metradiene is utilized as a research compound for studying its chemical properties, potential applications, and effects on biological systems. This helps scientists and researchers to better understand its role in the synthesis of Fluorometholone and explore its potential uses in other areas.
Used in Quality Control and Analysis:
Epoxy Metradiene serves as a reference compound in quality control and analysis processes to ensure the purity and effectiveness of Fluorometholone. It helps in monitoring the synthesis process and maintaining the desired quality standards for the final product.

Upstream product

• 110664-42-1 6α-methyl-17α-hydroxy-pregna-1,4,9(11)-triene-3,20-dione 

Downstream Products

• 426-13-1 fluorometholone 
• 83873-17-0 17α-acetoxy-6α-methyl-9β,11β-oxidopregna-1,4-dien-3,20-dione 

Relevant articles and documents

Chemoselective hydrogenation of 17α-hydroxy-6-methylen-pregna-4,9(11)-diene-3,20-dione. Synthesis of fluorometholone

The development of an efficient hydrogenation method of 17α-hydroxy-6-methylen-pregna-4,9(11)-diene-3,20-dione by using wet (10%) Pd on carbon and triethylamine led us to the corresponding 6α-methyl-pregnane in good yield. This chemoselective process allo