839673-82-4

Basic information

• Product Name: 2(1H)-Isoquinolinecarboxylic acid, 1-[(2-bromophenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 1,1-dimethylethyl ester
• CAS NO: 839673-82-4
• Molecular Formula: C23H28BrNO4
• Molecular Weight: 462.384
• Mol File: 839673-82-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(1H)-Isoquinolinecarboxylic acid, 1-[(2-bromophenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Isoquinolinecarboxylic acid, 1-[(2-bromophenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 1,1-dimethylethyl ester(839673-82-4)
• EPA Substance Registry System: 2(1H)-Isoquinolinecarboxylic acid, 1-[(2-bromophenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 1,1-dimethylethyl ester(839673-82-4)

Safety Data

• Hazardous Substances Data: 839673-82-4(Hazardous Substances Data)

Upstream product

• 18698-97-0 ortho-bromophenylacetic acid 
• 96557-30-1 2-bromophenylacetaldehyde 
• 98062-25-0 tert-butyl N-[2-(3,4-dimethoxyphenyl)ethyl]carbamate 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 80041-81-2 1-(2-bromobenzyl)-3,4-dihydro-6,7-dimethoxyisoquinoline 
• 109558-14-7 β-(3,4-dimethoxyphenyl)ethyl-(2'-bromophenyl)acetamide 
• 55116-09-1 2-bromophenylacetyl chloride 

Downstream Products

• 78946-24-4 1-(2-bromobenzyl)-N-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 5531-98-6 atherosperminine 
• 754919-24-9 C₂₀H₂₄NO₂⁽¹⁺⁾ 
• 69424-55-1 1,2-demethylnuciferine 

Relevant articles and documents

1-(2′-Bromobenzyl)-6,7-dihydroxy- N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors

Certain D2-like dopamine receptor (DR) agonists are useful therapeutically as antiparkinsonian drugs, whereas D2-like DR antagonists or partial agonists are proven effective as antipsychotics. Two isoquinoline derivatives, 1-(2′-brom

Total synthesis of (±)-armepavines and (±)-nuciferines from (2-nitroethenyl)benzene derivatives

A concise route to armepavine 1 and nuciferine 2 and 3, which can be isolated from the leaves of Nelumbo nucifera (Nymphaceae), has been achieved in which the longest linear sequence is only six steps from commercially available benzaldehyde in 28%, 21%, and 20% overall yield, respectively. The key transformations in the synthesis are the radical cyclization of aryl bromide with Bu3SnH and the Pictet-Spengler reaction of N-substituted amine with aldehyde. Copyright Taylor & Francis Group, LLC.