839698-01-0

Basic information

• Product Name: 2-Propynamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-3-[tris(1-methylethyl)silyl]-
• CAS NO: 839698-01-0
• Molecular Formula: C21H33NO2Si
• Molecular Weight: 359.584
• Mol File: 839698-01-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propynamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-3-[tris(1-methylethyl)silyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-3-[tris(1-methylethyl)silyl]-(839698-01-0)
• EPA Substance Registry System: 2-Propynamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-3-[tris(1-methylethyl)silyl]-(839698-01-0)

Safety Data

• Hazardous Substances Data: 839698-01-0(Hazardous Substances Data)

Upstream product

• 3182-95-4 L-Phenylalaninol 
• 839697-82-4 3-(triisopropylsilyl)propiolic acid 
• 89343-06-6 tris-iso-propylsilyl acetylene 

Downstream Products

• 326499-02-9 (4S)-4-benzyl-2-ethynyl-4,5-dihydrooxazole 

Relevant articles and documents

Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines

A method for the synthesis of 2-alkynyl oxazoles and oxazolines was discussed. These compounds were synthesized from readily available starting materials and were sufficiently polarized to participate in nucleophillic conjugate addition reactions. The addition of an acetate salt to the reaction mixture was found to be improving the overall yield. The conjugate addition reaction of heteronucleophiles to oxazole and oxazoline alkynes offers a versatile approach to produce heterocyclic building blocks for the synthesis of biologically active products.