84050-22-6

Basic information

• Product Name: 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE
• Synonyms: 2-PIPERAZINYL-4-AMINO-6,7-DIMETHOXYQUINAZOLINEHCL;4-Amino-2-piperazin-6,7-dimethoxyquinolinehydrochloride;2-Piperazinyl-6,7-dimethoxyquinazolin-4-amine hydrochlorode;Piperazine amino dimethoxy quinaoline hydrochloride;2-Piperazine-4-amino-6,7-dimethoxy quinazoline HCl;2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE;2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline Hydrochloride;2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINAOLINE HYDROCHLORIDE
• CAS NO: 84050-22-6
• Molecular Formula: C₁₄H₁₉N₅O₂*ClH
• Molecular Weight: 325.79
• Mol File: 84050-22-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 546.1 °C at 760 mmHg
• Flash Point: 284.1 °C
• Appearance: /
• Vapor Pressure: 2.92E-12mmHg at 25°C
• CAS DataBase Reference: 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE(84050-22-6)
• EPA Substance Registry System: 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE(84050-22-6)

Safety Data

• Hazardous Substances Data: 84050-22-6(Hazardous Substances Data)

Usage

General Description

2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE is a chemical compound that consists of a piperazine group and a quinoline ring with amino and dimethoxy substituents. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of potential therapeutic agents. This chemical has a range of biological activities, including anti-inflammatory, antimicrobial, and antiviral properties, making it a valuable building block for drug development. Additionally, the hydrochloride salt form of this compound provides improved solubility and stability, making it suitable for various pharmaceutical applications. Overall, 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE is a versatile chemical with potential therapeutic uses and is of interest for further research and development.

InChI:InChI=1/C14H19N5O2.ClH/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19;/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18);1H

Upstream product

• 23680-84-4 2-chloro-6,7-dimethoxyquinazolin-4-amine 
• 84050-21-5 4-amino-6,7-dimethoxy-2-(4-formylpiperazino)quinazoline hydrochloride 

Downstream Products

• 70842-87-4 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(3-trifluoromethyl-phenyl)-acryloyl]-piperazine 
• 117040-04-7 2-(4-cinnamoylpiperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline 
• 70842-79-4 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(2,3,4-trimethoxy-phenyl)-acryloyl]-piperazine 
• 84050-51-1 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(3-nitro-phenyl)-acryloyl]-piperazine 
• 70842-78-3 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(3,5-dimethoxy-phenyl)-acryloyl]-piperazine 
• 70842-70-5 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(4-isopropyl-phenyl)-acryloyl]-piperazine 
• 70842-85-2 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(3,4-dichloro-phenyl)-acryloyl]-piperazine 
• 70842-75-0 4-amino-2-<4-(4-ethoxycinnamoyl)piperazino>-6,7-dimethoxyquinazoline 
• 70842-73-8 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-[3-(4-methoxy-phenyl)-acryloyl]-piperazine 
• 84050-28-2 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-(3-m-tolyl-acryloyl)-piperazine 
• 70842-93-2 1-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-4-(3-furan-3-yl-acryloyl)-piperazine 

Relevant articles and documents

Pyrimidine Derivatives. 4. Synthesis and Antihypertensive Activity of 4-Amino-2-(4-cinnamoylpiperazino)-6,7-dimethoxyquinazoline Derivatives

A series of 30 4-amino-2-(4-cinnamoylpiperazino)-6,7-dimethoxyquinazoline derivatives was prepared and tested for their ability to reduce blood pressure in conscious, spontaneously hypertensive rats (SHR).A number of these compounds, notably 4-amino-2-(4-