840503-69-7Relevant articles and documents
Asymmetric synthesis of (R)-(+)-6-(1,4-dimethoxy-3-methyl-2-naphthyl)-6-(4- hydroxyphenyl)hexanoic acid as a key intermediate for a neurodegenerative disease agent
Ikemoto, Tomomi,Nagata, Toshiaki,Yamano, Mitsuhisa,Ito, Tatsuya,Mizuno, Yukio,Tomimatsu, Kiminori
, p. 7757 - 7760 (2007/10/03)
An asymmetric synthesis of (R)-(+)-6-(1,4-dimethoxy-3-methyl-2-naphthyl)-6- (4-hydroxyphenyl)hexanoic acid 2 as a key intermediate for a neurodegenerative disease agent 1 has been developed. A key reaction was an asymmetric hydrogenation of hindered acryl