84072-28-6

Basic information

• Product Name: (R)-1,3-Dimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester
• CAS NO: 84072-28-6
• Molecular Weight: 184.235
• Mol File: 84072-28-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-1,3-Dimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1,3-Dimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester(84072-28-6)
• EPA Substance Registry System: (R)-1,3-Dimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester(84072-28-6)

Safety Data

• Hazardous Substances Data: 84072-28-6(Hazardous Substances Data)

Upstream product

• 59416-90-9 methyl 3-methyl-2-oxocyclohexane-1-carboxylate 
• 74-88-4 methyl iodide 
• 2816-57-1 2,6-dimethylcyclohexanone 
• 7456-87-3 carbonic acid monomethyl ester 
• 66088-37-7 ethyl 1-methyl-2-oxocyclohexancarboxylate 
• 89656-82-6 methyl (-)-(R)-2-methyl-1-oxocyclohexane-2-carboxylate 
• 41302-34-5 2-(methoxycarbonyl)cyclohexanone 

Downstream Products

• 4884-89-3 <1,3-Dimethyl-1,3-dicarboxy-cyclohexyl-(2)-essigsaeure 
• 109040-12-2 (1,3-Dimethyl-3-methoxycarbonyl-cyclohexen-⁽¹⁾-yl)-essigsaeure 
• 100533-19-5 (1,3-Dimethyl-3-methoxycarbonyl-cyclohexen-⁽¹⁾-yl)-propionsaeure 
• 106591-27-9 (1,3-Dimethyl-3-methoxycarbonyl-cyclohexen-⁽¹⁾-yl)-propionsaeure-methylester 
• 109400-50-2 (1,3-Dimethyl-3-methoxycarbonyl-cyclohexen-⁽¹⁾-yl)-essigsaeure-ethylester 

Relevant articles and documents

Total Synthesis of -Mitrephorone A

The first synthesis of mitrephorone A is disclosed along with discussion and study of synthetic strategies. The natural product includes a highly congested hexacyclic ent-trachylobane diterpenoid framework featuring a rare, embedded oxetane. The synthetic analysis presented dissects a number of approaches for the synthesis of the central oxetane, including carbonyl-olefin photocycloadditions, Prins-type cyclizations, and oxidative ring closures. In the successful route, three [4 + 2] cycloadditions enable rapid construction of all carbocycles. A novel late-stage oxidative cyclization of a hydroxy diosphenol with Koser's reagent furnishes the pivotal oxetane moiety.

Total Synthesis of (+/-)-Methyl Phaseates

(+/-)-Methyl phaseates were synthesized from (+/-)-4-(6'-acetoxymethyl-2'-6'-dimethyl-1'-cyclohexen-1'-yl)-but-3-en-2-one (20), which was prepared from a useful terpenoid building block, (+/-)-2-hydroxymethyl-2,6-dimethyl-1-cyclohexanone (11a and 11b).Pho