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842162-99-6

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842162-99-6 Usage

Description

4-tert-ButyldiMethylsilyl Atorvastatin Lactone is a chemical derivative of Atorvastatin Lactone (A791780), which is a key intermediate in the synthesis of atorvastatin, a widely used cholesterol-lowering drug.
Used in Pharmaceutical Industry:
4-tert-ButyldiMethylsilyl Atorvastatin Lactone is used as a chemical intermediate for the preparation of N-substituted pyrrole derivatives, which are crucial in the synthesis of atorvastatin. This application is significant in the development and production of cholesterol-lowering medications, contributing to the treatment and management of cardiovascular diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 842162-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,2,1,6 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 842162-99:
(8*8)+(7*4)+(6*2)+(5*1)+(4*6)+(3*2)+(2*9)+(1*9)=166
166 % 10 = 6
So 842162-99-6 is a valid CAS Registry Number.

842162-99-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,4R)-1-{2-[4-(tert-butyldimethylsilyloxy)-6-oxotetrahydro-2-pyranyl]-ethyl}-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

1.2 Other means of identification

Product number -
Other names 4-tert-Butyldimethylsilyl Atorvastatin Lactone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:842162-99-6 SDS

842162-99-6Relevant articles and documents

Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives

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Page/Page column 29-30, (2010/11/28)

The present invention relates to a process for preparing C7 intermediates and their use in the preparation of pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids. The invention further relates to intermediates in this process.

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