84219-92-1Relevant articles and documents
Novel peptidyl carbamate inhibitors of the enzyme elastase
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, (2008/06/13)
Compounds selected from the group consisting of a compound of the formula STR1 and compound of the formula STR2 wherein x is 1 or 2, Y is carbobenzoxy or benzoyl, and XR is STR3 have use as elastase enzyme inhibitors. Particularly potent are the L-proline diastereomers. Elastase Enzyme inhibitory compositions comprise a carrier and an elastase enzyme inhibiting amount of the compounds of the invention. A method of selectively inhibiting the enzyme elastase in an animal or a human in need of such treatment comprises administering to the animal or human an enzyme elastase inhibiting amount of one of the compounds of the invention or a composition thereof.