84248-95-3Relevant articles and documents
First example of molecular iodine-catalyzed allylation and alkynylation of cyclic allylic acetates
Yadav,Reddy,Rao, K. Vishweshwar,Raj, K. Sarita,Rao, P. Purushothama,Prasad,Gunasekar
, p. 6505 - 6507 (2004)
Cyclic allylic acetates undergo smooth allylation and alkynylation with allyltrimethylsilane and alkynyl silanes in the presence of molecular iodine under mild conditions to afford the corresponding allylated and alkynylated cyclohexene derivatives in goo
Allylic C-H Alkynylation via Copper-Photocatalyzed Cross-Dehydrogenative Coupling
Almasalma, Ahmad A.,Mejía, Esteban
, p. 529 - 536 (2020/02/13)
An efficient, novel photocatalyzed allylic-alkynylation methodology via copper-based cross-dehydrogenative coupling (CDC) is described. Different types of 1,4-enyne compounds were synthesized in one step at room temperature using copper(I) terpyridyl comp
Copper-Catalyzed Allylic C?H Alkynylation by Cross-Dehydrogenative Coupling
Almasalma, Ahmad A.,Mejía, Esteban
supporting information, p. 12269 - 12273 (2018/08/28)
C?H bond functionalization is a well-developed concept that has been thoroughly studied and gives entry to rather complex molecules without the need for previous derivatization of the substrates. The use of copper complexes in allylic C?H bond functionalization under oxidative conditions as an alternative to the well-established palladium-based methodologies remains largely underdeveloped. Here, we show for the first time a selective cross-dehydrogenative coupling reaction between underivatized allylic substrates and terminal alkynes to produce 1,4-enynes in high yields in a single step, using an in situ synthesized copper catalyst and an oxidant.
