84324-68-5

Basic information

• Product Name: 4-bromo-N-(pyridin-3-ylmethyl)aniline
• Synonyms: 4-bromo-N-(pyridin-3-ylmethyl)aniline;N-(4-Bromophenyl)-3-pyridinemethanamine;3-PyridineMethanaMine, N-(4-broMophenyl)-;4-BroMo-N-(pyridin-3-ylMethyl)benzenaMine
• CAS NO: 84324-68-5
• Molecular Formula: C₁₂H₁₁BrN₂
• Molecular Weight: 263.13
• Mol File: 84324-68-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.4 °C at 760 mmHg
• Flash Point: 183.9 °C
• Appearance: /
• Density: 1.470
• Vapor Pressure: 5.45E-06mmHg at 25°C
• Refractive Index: 1.66
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-bromo-N-(pyridin-3-ylmethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-N-(pyridin-3-ylmethyl)aniline(84324-68-5)
• EPA Substance Registry System: 4-bromo-N-(pyridin-3-ylmethyl)aniline(84324-68-5)

Safety Data

• Hazardous Substances Data: 84324-68-5(Hazardous Substances Data)

Usage

General Description

4-bromo-N-(pyridin-3-ylmethyl)aniline is a chemical compound that contains a bromine atom, a pyridine ring, and an aniline group. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-bromo-N-(pyridin-3-ylmethyl)aniline has potential applications in medicinal chemistry and can be used as a building block in the development of new drugs. It is important to handle this compound with care, as it may have hazardous properties and should be used in a controlled laboratory setting. Overall, 4-bromo-N-(pyridin-3-ylmethyl)aniline is a versatile and valuable chemical compound with various potential applications in the field of chemistry and drug development.

InChI:InChI=1/C12H11BrN2/c13-11-3-5-12(6-4-11)15-9-10-2-1-7-14-8-10/h1-8,15H,9H2

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 586-78-7 para-nitrophenyl bromide 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 353235-63-9 N-[4-(2-methoxyphenoxy)phenyl]pyridin-3-ylmethylamine 

Relevant articles and documents

MOF-derived cobalt nanoparticles catalyze a general synthesis of amines

The development of base metal catalysts for the synthesis of pharmaceutically relevant compounds remains an important goal of chemical research. Here, we report that cobalt nanoparticles encapsulated by a graphitic shell are broadly effective reductive amination catalysts. Their convenient and practical preparation entailed template assembly of cobaltdiamine- dicarboxylic acid metal organic frameworks on carbon and subsequent pyrolysis under inert atmosphere.The resulting stable and reusable catalysts were active for synthesis of primary, secondary, tertiary, and N-methylamines (more than 140 examples).The reaction couples easily accessible carbonyl compounds (aldehydes and ketones) with ammonia, amines, or nitro compounds, and molecular hydrogen under industrially viable and scalable conditions, offering cost-effective access to numerous amines, amino acid derivatives, and more complex drug targets.

Potentiators of glutamate receptors

The present invention relates to potentiators of metabotropic glutamate receptor function and specifically provides compounds of formula I, compositions thereof and methods of using the same.