84337-43-9 Usage
Description
1-O-Octadecyl-2-O-methyl-rac-glycerol is a complex glycerol derivative with a unique molecular structure featuring an octadecyl chain and a methyl group. 1-O-OCTADECYL-2-O-METHYL-RAC-GLYCEROL serves as a key intermediate in the synthesis of various bioactive molecules, particularly those with potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-O-Octadecyl-2-O-methyl-rac-glycerol is used as a precursor for the synthesis of Edelfosine, a potent inducer of apoptosis in human leukemic cells. Edelfosine has garnered significant attention as a promising drug candidate in cancer treatment, particularly for hematological malignancies.
Additionally, 1-O-Octadecyl-2-O-methyl-rac-glycerol is utilized in the preparation of phospholipids containing nitrogen homologs, which exhibit antitumor activities. These phospholipids have potential applications in the development of novel therapeutic agents targeting cancer cells, further highlighting the versatility and importance of this glycerol derivative in the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 84337-43-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,3 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 84337-43:
(7*8)+(6*4)+(5*3)+(4*3)+(3*7)+(2*4)+(1*3)=139
139 % 10 = 9
So 84337-43-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H46O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25-21-22(20-23)24-2/h22-23H,3-21H2,1-2H3
84337-43-9Relevant articles and documents
Synthese sowie Antitumorwirksamkeit und Vertraeglichkeit im Tierexperiment von elementhomologen Phospholipiden
Stekar, Jurij,Noessner, Gerhard,Kutscher, Bernhard,Engel, Juergen,Hilgard, Peter
, p. 195 - 197 (2007/10/02)
Stichworte: Antitumormittel * Phospholipide
Synthesis of alkyl glycerophospholipids through 1-o-benzyl-2-o-methyl-rac-glycerol
Pinchuk,Mitsner,Shvets
, p. 174 - 176 (2007/10/02)
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Nucleoside conjugates. 7. Synthesis and antitumor activity of 1-β-D-arabinofuranosylcytosine conjugates of ether lipids
Hong,An,Buchheit,Nechaev,Kirisits,West,Berdel
, p. 2038 - 2044 (2007/10/02)
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